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Research Article

Blood pressure monitoring via double sandwich-structured triboelectric sensors and deep learning models

Xu Ran1, Fangyuan Luo1, Zhiming Lin1, Zhiyuan Zhu1, Chuanjun Liu2, Bin Chen1( )
Chongqing Key Laboratory of Non-linear Circuit and Intelligent Information Processing, College of Electronic and Information Engineering, Southwest University, Chongqing 400715, China
Research Laboratory, U.S.E. Co., Ltd., Shibuya-ku, Tokyo 150-0013, Japan
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Abstract

Real-time blood pressure monitoring is essential for the timely diagnosis and treatment of cardiovascular disease. Many traditional prediction methods estimate blood pressure by measuring multiple sets of physiological signals with energy-consuming sensors. Herein, a continuous, cuffless and self-powered blood pressure monitoring system was developed based on a new double sandwich-structured triboelectric sensor and a novel blood pressure method estimation. A pyramid-patterned sensor based on the double sandwich structure realizes a sensitivity of 0.89 V/kPa in a linear range of 0–35 kPa, which is more than twice of the conventional single electrode structure. The sensor processes a low pressure detection limit of 1 g andfast response time of 32 ms. Hence, it can easily capture the pulse signal at the radial artery. Furthermore, a novel method for estimating blood pressure using pulse waves accompanied by the user’s background information was proposed. This method measures only one set of pulse signals and is portable. A deep learning model with multi-network structures was developed to improve the estimation accuracy. The mean absolute error and standard deviation of error for systolic and diastolic blood pressure (SBP and DBP) estimations were 3.79 ± 5.27 and 3.86 ± 5.18 mmHg, respectively. This work reveals a new sensing structure of triboelectric sensors and offers a novel method for blood pressure estimation.

Graphical Abstract

A continuous, cuffless and self-power blood pressure monitoring system was developed based on anew double sandwich-structured triboelectric sensor and a novel blood pressure method estimation.

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Nano Research
Pages 5500-5509

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Cite this article:
Ran X, Luo F, Lin Z, et al. Blood pressure monitoring via double sandwich-structured triboelectric sensors and deep learning models. Nano Research, 2022, 15(6): 5500-5509. https://doi.org/10.1007/s12274-022-4172-2
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Received: 26 November 2021
Revised: 15 January 2022
Accepted: 19 January 2022
Published: 15 March 2022
© Tsinghua University Press 2022