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Multi-zone modeling of airflow in a free running building floor: Possible implications for disease transmission

Eric Schuldenfrei2Xu Tang3,4Xi Deng2,3Qun Wang5,#Zhang Lin6Jianxiang Huang1( )
Institute of Future Human Habitats, Tsinghua University Shenzhen International Graduate School, Shenzhen, China
Department of Architecture, The University of Hong Kong, Hong Kong, China
Department of Urban Planning and Design, The University of Hong Kong, Hong Kong, China
The University of Hong Kong Shenzhen Institute of Research and Innovation, Shenzhen 518057, China
Department of Mechanical Engineering, The University of Hong Kong, Hong Kong, China
Department of Architecture and Civil Engineering, City University of Hong Kong, Hong Kong, China

# Present address: Department of Environmental Science and Engineering, Macau University of Science and Technology, Macau, China

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Abstract

Free running buildings are suspected of spreading viral aerosols from unit to unit; while modeling literature is limited in analyzing multi-zone airflow influenced by a large number of building openings. Question remains as whether windows or doors should be closed to mitigate hazard transmission in such conditions? This study aims to (1) model the multi-zone airflow in a large free running building, and (2) present intermediary evidence on the possible disease transmission associated with such flow. A COVID-19 outbreak in a high-rise apartment building in Hong Kong was investigated. A cascading strategy was developed to backcalculate the unit-to-unit airflows and hazard concentration. The model was partially evaluated using tracer-gas experiments conducted using 3D-printed mockup building placed inside a wind tunnel. Findings suggest that hazard emanating from the source unit are likely to migrate downwind through both indoor and outdoor pathways. Closing windows can reduce such risk by a factor of two to four. The cascading strategy can analyze airflow in a complex building with surrounding urban and topological context. The public health message is that windows and doors should be closed during hazard outbreaks such as fire, smoke, or infectious diseases.

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Building Simulation
Pages 587-603

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Cite this article:
Schuldenfrei E, Tang X, Deng X, et al. Multi-zone modeling of airflow in a free running building floor: Possible implications for disease transmission. Building Simulation, 2026, 19(3): 587-603. https://doi.org/10.1007/s12273-026-1417-0

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Received: 05 September 2025
Revised: 06 January 2026
Accepted: 14 January 2026
Published: 17 March 2026
© Tsinghua University Press 2026