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The traditional ventilation aims to create a uniform indoor environment, which neglects the diverse thermal requirements of different locations within large-space building, resulting in significant energy waste. This study proposes a method based on partition control using column attachment ventilation to create a non-uniform indoor environment under cooling conditions. The main factors influencing thermal environment differences among zones were identified through orthogonal experiments, and the effects of partition control on indoor convective heat transfer and thermal comfort were analyzed. A 1:4 scale model was used to conduct temperature field verification experiments. The results indicate that under the column attachment ventilation mode, partition control can create a non-uniform environment, enhancing indoor temperature non-uniformity by 3.67 times compared to uniform ventilation. The factors influencing zonal thermal environment differences are air supply temperature difference (

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