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Editorial | Open Access

Clinical Breakthrough in Targeted Protein Degradation: Reflections on the Approval of ARV‐471

Yu Rao1,2( )
MOE Key Laboratory of Protein Sciences, School of Pharmaceutical Sciences, MOE Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, State Key Laboratory of Molecular Oncology, Tsinghua University, Beijing, China
Beijing Key Laboratory of Targeted Protein Degradation and Molecular Glue Therapeutics, Tsinghua University, Beijing, China
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Keywords

breast cancerprotactargeted protein degradationvepdegestrant

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Cancer Innovation
Volume 5 Issue 3,
June 2026
Article number: e70068
DOI: 10.1002/cai2.70068

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Cite this article:
Rao Y. Clinical Breakthrough in Targeted Protein Degradation: Reflections on the Approval of ARV‐471. Cancer Innovation, 2026, 5(3): e70068. https://doi.org/10.1002/cai2.70068

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Received: 18 May 2026
Accepted: 18 May 2026
Published: 07 June 2026
© 2026 The Author(s). Tsinghua University Press.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.