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Lung cancer is the malignant tumor with the highest morbidity and mortality in China, and nonsmall cell lung cancer is a common form of lung cancer. After undergoing chemotherapy and molecular targeted therapy, the treatment of lung cancer has now fully entered the era of immunotherapy. Immunotherapy‐based treatment has become one of the standard treatments for lung cancer. Immunotherapy has also gradually moved from the back line to the front line, from advanced to early patients. This article focuses on the latest developments in perioperative and advanced lung cancer immunotherapy, discusses the problems and challenges at the current stage, and explores new directions for future development.


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Advances in medical treatment of breast cancer in 2022

Show Author's information Jingtong Zhai1Yun Wu1Fei Ma1 ( )Virginia Kaklamani2 ( )Binghe Xu1 ( )
Department of Medical Oncology, National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
Division of Hematology, Oncology, UT Health San Antonio MD Anderson Cancer Center, San Antonio, Texas, USA

Jingtong Zhai and Yun Wu contributed equally to this work and shared the first authorship.

Abstract

Lung cancer is the malignant tumor with the highest morbidity and mortality in China, and nonsmall cell lung cancer is a common form of lung cancer. After undergoing chemotherapy and molecular targeted therapy, the treatment of lung cancer has now fully entered the era of immunotherapy. Immunotherapy‐based treatment has become one of the standard treatments for lung cancer. Immunotherapy has also gradually moved from the back line to the front line, from advanced to early patients. This article focuses on the latest developments in perioperative and advanced lung cancer immunotherapy, discusses the problems and challenges at the current stage, and explores new directions for future development.

Keywords: nonsmall cell lung cancer, small cell lung cancer, perioperative period, late stage, new immunotherapy

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Received: 16 November 2022
Accepted: 18 December 2022
Published: 21 February 2023
Issue date: February 2023

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© 2023 The Authors. Cancer Innovation published by John Wiley & Sons Ltd. on behalf of Tsinghua University Press.

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