Report title: Cellular intelligence against adversity to enhance energy saving and consumption in biomanufacturing

He is a tenured professor of the Department of Chemical Engineering of Tsinghua University, director of the Institute of Biochemical Engineering, and director of the Key Laboratory of Industrial Biocatalysis of the Ministry of Education. He has been engaged in the research of metabolic engineering and synthetic biology, biocatalysis and enzyme engineering for a long time, focusing on the enzymatic transformation and microbial synthesis of terpenes and flavonoids natural products, and the design and engineering application of intelligent anti-stress molecules for industrial strains. In 2006, he enjoyed the special government allowance of the State Council. In 2014, he won the National Science Fund for Distinguished Young Scholars. In 2017, he won the "Hou Debang Chemical Technology Innovation Award". Chief Scientist of "Synthetic Biology". It has completed the pilot test of the enzymatic degumming of vegetable oil, the biological production of glycyrrhetic acid, and the fermentation of multiple heat-resistant yeast to produce ethanol. He has published nearly 300 papers in ACS Catal, ACS Energy Lett, Nature Commun, MetabolicEng, ACS Synth Biol, AIChEJ, ChemEngSci, JBiolChem, JPhyChemLetter and other journals, H-index=42, 36 authorized invention patents, and 4 provincial and ministerial level scientific and technological achievement awards. He has edited 11 chapters of textbooks and monographs, among which "Synthetic Biology" and "Introduction to Bioengineering and Technology" as the chief editor won the first prize for ministerial excellent teaching materials, and "Biochemistry" as the deputy editor has become a widely used teaching material in colleges and universities. He is currently the deputy director of the Biochemical Special Committee of the Chinese Chemical Society and the deputy director of the Synthetic Biology Branch of the Chinese Society of Bioengineering. He is the executive editor of Synthetic Biology, the deputy editor of FrontiersinBioengBiotechnol, AppliedMicrobioBiotechnol, SynthSystemBiotechnol, and Progress in Chemical Industry. ", "Journal of Catalysis", "Chinese Journal of Process Engineering", "Chinese Journal of Agricultural Engineering", "Bioprocessing" and other journals editorial board.