Genes & Diseases

ISSN 2352-4820 e-ISSN 2352-3042 CN 50-1221/R

Editors-in-Chief: Ailong Huang, Tong-Chuan He

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Keyword: targeted therapy

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Open Access Review Article

LKB1 tumor suppressor: Therapeutic opportunities knock when LKB1 is inactivated

Wei Zhou, Jun Zhang, Adam I. Marcus

https://doi.org/10.1016/j.gendis.2014.06.002

Published: 23 July 2014

2014, 1 (1): 64-74

Downloads: 3 | Views: 129 |

PDF (1 MB)

Open Access Review Article

Drugging IGF-1R in cancer: New insights and emerging opportunities

Panpan Wang, Victor CY. Mak, Lydia WT. Cheung

https://doi.org/10.1016/j.gendis.2022.03.002

Published: 23 March 2022

2023, 10 (1): 199-211

Downloads: 1 | Views: 170 |

PDF (1.3 MB)

Open Access Review Article

Non-small cell lung carcinoma (NSCLC): Implications on molecular pathology and advances in early diagnostics and therapeutics

Hafiza Padinharayil, Jinsu Varghese, Mithun Chacko John, [...], Golgodu Krishnamurthy Rajanikant, Cornelia M. Wilson, Minnatallah Al-Yozbaki, Kaviyarasi Renu, Saikat Dewanjee, Rupa Sanyal, Abhijit Dey, Anirban Goutam Mukherjee, Uddesh Ramesh Wanjari, Abilash Valsala Gopalakrishnan, Alex George << Fewer

https://doi.org/10.1016/j.gendis.2022.07.023

Published: 23 August 2022

2023, 10 (3): 960-989

Downloads: 3 | Views: 132 |

PDF (3.3 MB)

Open Access Review Article

HIF-1α signaling: Essential roles in tumorigenesis and implications in targeted therapies

Yan Zhao, Cheng Xing, Yating Deng, [...], Can Ye, Hongling Peng << Fewer

https://doi.org/10.1016/j.gendis.2023.02.039

Published: 30 March 2023

2024, 11 (1): 234-251

Downloads: 2 | Views: 71 |

PDF (2.2 MB)

Open Access Full Length Article

Colony-stimulating factor-1 receptor inhibition combined with paclitaxel exerts effective antitumor effects in the treatment of ovarian cancer

Meijia Yu, Yiming Wu, Qingfang Li, [...], Weiqi Hong, Yang Yang, Xiaoyi Hu, Yanfei Yang, Tianqi Lu, Xia Zhao, Xiawei Wei << Fewer

https://doi.org/10.1016/j.gendis.2023.04.023

Published: 22 June 2023

2024, 11 (3): 100989

Downloads: 2 | Views: 31 |

PDF (5 MB)

Open Access Review Article

The evolving roles of Wnt signaling in stem cell proliferation and differentiation, the development of human diseases, and therapeutic opportunities

Michael Yu, Kevin Qin, Jiaming Fan, [...], Guozhi Zhao, Piao Zhao, Wei Zeng, Connie Chen, Annie Wang, Yonghui Wang, Jiamin Zhong, Yi Zhu, William Wagstaff, Rex C. Haydon, Hue H. Luu, Sherwin Ho, Michael J. Lee, Jason Strelzow, Russell R. Reid, Tong-Chuan He << Fewer

https://doi.org/10.1016/j.gendis.2023.04.042

Published: 22 July 2023

2024, 11 (3): 101026

Downloads: 2 | Views: 41 |

PDF (2.9 MB)

Open Access Review Article

Mutant KRAS as a critical determinant of the therapeutic response of colorectal cancer

Kyle Knickelbein, Lin Zhang

https://doi.org/10.1016/j.gendis.2014.10.002

Published: 01 November 2014

2015, 2 (1): 4-12

Downloads: 1 | Views: 144 |

PDF (874.1 KB)

Open Access Review Article

Genetics on early onset inflammatory bowel disease: An update

Johnson Nameirakpam, Rashmi Rikhi, Sanjay Singh Rawat, [...], Jyoti Sharma, Deepti Suri << Fewer

https://doi.org/10.1016/j.gendis.2019.10.003

Published: 15 October 2019

2020, 7 (1): 93-106

Downloads: 5 | Views: 181 |

PDF (1.3 MB)

Open Access Review Article

Targeting LIF/LIFR signaling in cancer

Suryavathi Viswanadhapalli, Kalarickal V. Dileep, Kam Y.J. Zhang, [...], Hareesh B. Nair, Ratna K. Vadlamudi << Fewer

https://doi.org/10.1016/j.gendis.2021.04.003

Published: 29 April 2021

2022, 9 (4): 973-980

Downloads: 4 | Views: 208 |

PDF (1.6 MB)

Open Access Review Article

Melanoma: Molecular genetics, metastasis, targeted therapies, immunotherapies, and therapeutic resistance

William Wagstaff, Rimel N. Mwamba, Karina Grullon, [...], Mikhayla Armstrong, Piao Zhao, Bryce Hendren-Santiago, Kevin H. Qin, Alexander J. Li, Daniel A. Hu, Andrew Youssef, Russell R. Reid, Hue H. Luu, Le Shen, Tong-Chuan He, Rex C. Haydon << Fewer

https://doi.org/10.1016/j.gendis.2022.04.004

Published: 27 April 2022

2022, 9 (6): 1608-1623

Downloads: 3 | Views: 295 |

PDF (3.2 MB)

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