Guest Editors

Prof. Lijun You

School of Food Science and Engineering

South China University of Technology, Guangzhou, China

E-mail: feyoulijun@scut.edu.cn

Prof. Rong Liu

Department of nutrition and health

China agricultural university, Beijing, China

E-mail: feyoulijun@scut.edu.cn

Prof. Yucun Niu

Department of Nutrition and Food Hygiene, School of Public Health, Harbin Medical University, Harbin, China

E-mail: niuyucun@hrbmu.edu.cn

Prof. Wenzhen liao

School of Public Health

Southern Medical University, Guangzhou, China

E-mail: wenzhenliao@163.com

Description

Diet plays an important role in maintaining health and preventing chronic diseases. However, individuals and population groups can respond differently to the same food or dietary intervention. These responses depend not only on food composition and structure but also on host physiology, metabolism, and the gut microbiota. Understanding these interactions can help explain why responses differ and inform dietary strategies tailored to different nutritional needs.

Precision nutrition considers these host characteristics alongside dietary habits and lifestyle. It uses this information to assess nutritional needs and design targeted interventions for individuals and population groups. Recent advances in food biochemistry, molecular nutrition, microbiology, and multi-omics have provided novel technologies for investigating the physiological functions of food components and variation in dietary responses. These developments also help elucidate the mechanisms underlying interindividual variability in nutritional responses. Such mechanistic insights can identify suitable target populations, provide intake recommendations, and design tailored dietary interventions.

Food Science and Human Wellness is therefore pleased to announce a Special Issue entitled “Precision Nutrition for Chronic Disease Prevention.” The Special Issue will promote collaboration across food science, nutrition, microbiology, and immunology to examine food component functions, nutritional response differences, and dietary interventions for different populations. By linking mechanistic insights, intervention design, and population health research, it aims to strengthen the scientific basis for precision nutrition interventions and functional food development.

The scope of this Special Issue includes, but is not limited to:

• Functions and Mechanisms of Dietary Bioactive Components: Research on the biological functions of dietary bioactive components, including structure–activity relationships, bioavailability, and mechanisms underlying effects on metabolism and immunity under different physiological conditions.
• Food Composition, Structure, and Nutritional Effects: Research examining how food composition and structure affect digestion and bioavailability, including component interactions, changes induced by processing or fermentation, and food design and delivery strategies to improve nutrient utilization.
• Food–Gut Microbiota Interactions and Host Health: Research on interactions between food components and gut microbiota, including microbial transformation, effects of microbial metabolites on host metabolism and immunity, and links between microbiota profiles and intervention responses.
• Functional Foods and Targeted Dietary Interventions: Development and evaluation of functional foods and dietary interventions for specific populations, including identification of suitable target populations, prediction of nutritional responses, and evaluation of effectiveness in preventing chronic diseases.

This Special Issue welcomes original research and review articles on dietary bioactive components and its role in precision nutrition and chronic disease prevention. We encourage contributions that explain differences in nutritional responses and inform targeted dietary strategies and functional food development for chronic disease prevention.

Keywords

Precision nutrition; Chronic disease prevention; Functional foods; Dietary intervention

Submission Guidelines

• Manuscript Type: Precision Nutrition for Chronic Disease Prevention (please select this article type during submission).
• Submission Deadline: May 31, 2027
• Expected Publication Date: November 30, 2027
• Online Submission System: https://mc03.manuscriptcentral.com/fshw
• Editorial Office Email: fshw@foodsci.cn