Genes & Diseases

ISSN 2352-4820 e-ISSN 2352-3042 CN 50-1221/R
Editors-in-Chief: Ailong Huang, Tong-Chuan He
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Volume 10
Issue 4, July 2023
pp.1131-1725 57 articles
Contents(PDF)
RESEARCH HIGHLIGHT
Open Access Research Highlight
The key piece of the airway remodeling puzzle revealed—LIGHT signaling in the lung
Ziyan Rachel Chen, Jim Hu
https://doi.org/10.1016/j.gendis.2023.02.021
Published: 27 March 2023
2023, 10 (4): 1131-1132
Downloads: 3 | Views: 118 | PDF (625.5 KB)
COMMENTARIES
Open Access Commentary
Herpesviral interplay with peroxisome: An underexplored viral niche
Omkar Indari, Süleyman Ergün, Srikanth Karnati, Hem Chandra Jha
https://doi.org/10.1016/j.gendis.2023.01.033
Published: 24 March 2023
2023, 10 (4): 1133-1135
Downloads: 2 | Views: 95 | PDF (894.1 KB)
Open Access Commentary
Cancer exploits a late premetazoan gene module conserved in the human genome
Vladimir F. Niculescu
https://doi.org/10.1016/j.gendis.2023.01.020
Published: 28 March 2023
2023, 10 (4): 1136-1138
Downloads: 5 | Views: 104 | PDF (451.5 KB)
Open Access Commentary
A comment on the article of Zoran Ivanovic and Marija Vlaski-Lafarge (2022): On cancer, stemness and deep evolutionary homologies
Vladimir F. Niculescu
https://doi.org/10.1016/j.gendis.2022.11.004
Published: 10 December 2022
2023, 10 (4): 1139-1140
Downloads: 2 | Views: 76 | PDF (225.8 KB)
CORRESPONDENCES
Open Access Correspondence
False discovery rate control in cancer biomarker selection
Zhaoming Li
https://doi.org/10.1016/j.gendis.2022.12.010
Published: 25 October 2023
2023, 10 (4): 1141-1142
Downloads: 4 | Views: 187 | PDF (218.6 KB)
Open Access Correspondence
On cancer, stemness, and deep evolutionary homologies
Zoran Ivanovic, Marija Vlaski-Lafarge
https://doi.org/10.1016/j.gendis.2023.01.003
Published: 21 April 2023
2023, 10 (4): 1143-1144
Downloads: 2 | Views: 102 | PDF (223 KB)
Open Access Correspondence
Correspondence (reply): The application conditions of false discovery rate control
Hongbin Zhang, Xin Le, Tingxiu Xiang
https://doi.org/10.1016/j.gendis.2022.11.011
Published: 25 October 2023
2023, 10 (4): 1145-1146
Downloads: 6 | Views: 182 | PDF (219.4 KB)
RAPID COMMUNICATIONS
Open Access Rapid Communication
Inhibition of VEGFR2 overcomes venetoclax-resistance in diffuse large B-cell lymphoma cells
Yuanfei Shi, Yi Xu, Wanzhuo Xie
https://doi.org/10.1016/j.gendis.2022.07.012
Published: 05 August 2022
2023, 10 (4): 1147-1149
Downloads: 2 | Views: 103 | PDF (871.7 KB)
Open Access Rapid Communication
Atrial Septal Defect (ASD) associated long non-coding RNA STX18-AS1 maintains time-course of in vitro cardiomyocyte differentiation
Yingjuan Liu, Mun-kit Choy, Sabu Abraham, [...], Gennadiy Tenin, Graeme C. Black, Bernard D. Keavney << Fewer
https://doi.org/10.1016/j.gendis.2022.07.010
Published: 08 August 2022
2023, 10 (4): 1150-1153
Downloads: 2 | Views: 96 | PDF (870.5 KB)
Open Access Rapid Communication
EBV-Mir-BART5-5p targets p53 independent pathway in cytoplasm: Potential role in EBV lymphomagenesis
Wei-Ting Wang, Jing-Ran Guo, Li Wang, [...], Jia-Zhu Wu, Hao-Rui Shen, Yi-Lin Kong, Yi Xia, Jian-Yong Li, Jin-Hua Liang, Wei Xu << Fewer
https://doi.org/10.1016/j.gendis.2022.07.003
Published: 19 August 2022
2023, 10 (4): 1154-1156
Downloads: 4 | Views: 106 | PDF (643.7 KB)
Open Access Rapid Communication
Human RNA Modifications Disease Database (HRMDD): A web resource for the molecular and clinical landscape of RNA modifications in human diseases
Jianjian Wang, Lifang Li, Hanxiao Zhou, [...], Shuang Li, Liting Tian, Xinyue Wang, Danyang Li, Yue Yin, Shangwei Ning, Lihua Wang << Fewer
https://doi.org/10.1016/j.gendis.2022.08.024
Published: 10 September 2022
2023, 10 (4): 1157-1160
Downloads: 2 | Views: 84 | PDF (1.2 MB)
Open Access Rapid Communication
SV40 large T antigen-induced immortalization reprograms mouse cardiomyocyte progenitors with mesenchymal stem cell characteristics and osteogenic potential
Yichun Yu, Jiamin Zhong, Connie Chen, [...], Yannian Gou, Guozhi Zhao, Piao Zhao, Yonghui Wang, Wei Zeng, Annie Wang, William D. Wagstaff Jr., Rex C. Haydon, Tong-Chuan He, Russell R. Reid, Michael J. Lee, Hue H. Luu, Jiaming Fan << Fewer
https://doi.org/10.1016/j.gendis.2022.10.008
Published: 21 October 2022
2023, 10 (4): 1161-1164
Downloads: 3 | Views: 126 | PDF (1.5 MB)
Open Access Rapid Communication
A homozygous nonsense mutation in DNAJC30 causes Leber's hereditary optic neuropathy with Leigh-like phenotypes
Chao Shen, Kitty Wang, Wei Li, [...], Alvaro Serrano, Kelly Powers, Chengwan Zhang, Jianjun Chen, Miao Sun << Fewer
https://doi.org/10.1016/j.gendis.2022.09.011
Published: 06 October 2022
2023, 10 (4): 1165-1168
Downloads: 3 | Views: 111 | PDF (854.4 KB)
Open Access Rapid Communication
The modifying influence of HLA class Ⅱ DQB1*06:02 on the Streptococcus and clinical phenotype correlation among anti-Ro+ mothers of children with neonatal lupus
Robert M. Clancy, Carla J. Guthridge, Miranda C. Marion, [...], Joel Guthridge, Timothy D. Howard, Peter M. Izmirly, Mala Masson, Jill P. Buyon, Judith A. James, Carl D. Langefeld << Fewer
https://doi.org/10.1016/j.gendis.2022.11.006
Published: 13 December 2022
2023, 10 (4): 1169-1171
Downloads: 2 | Views: 100 | PDF (448.3 KB)
Open Access Rapid Communication
Aberrant cholesterol metabolism in colorectal cancer represents a targetable vulnerability
Jingwu Xie, Chi Mai Nguyen, Anita Turk, [...], Hongmei Nan, Thomas F. Imperiale, Michael House, Kun Huang, Jing Su << Fewer
https://doi.org/10.1016/j.gendis.2022.06.002
Published: 26 June 2022
2023, 10 (4): 1172-1174
Downloads: 2 | Views: 128 | PDF (624.9 KB)
Open Access Rapid Communication
Bone Morphogenic Protein 9 (BMP9)/Growth Differentiation Factor 2 (GDF2) modulates mouse adult hippocampal neurogenesis by regulating the survival of early neural progenitors
Mary Rose Rogers, Wei Zeng, Xian Zhang, [...], Ruidong Li, Qiang Wei, Yuhan Kong, Piao Zhao, Guozhi Zhao, Yonghui Wang, Jiamin Zhong, Yi Zhu, Rex C. Haydon, Hue H. Luu, Russell R. Reid, Daniel A. Peterson, Michael J. Lee, Tong-Chuan He << Fewer
https://doi.org/10.1016/j.gendis.2023.02.018
Published: 29 March 2023
2023, 10 (4): 1175-1179
Downloads: 3 | Views: 95 | PDF (1 MB)
Open Access Rapid Communication
Regulatory effects of miR-19a on MAD2 expression and tumorigenesis in gastric cancer
J. Bargiela-Iparraguirre, J.M. Herrero, N. Pajuelo-Lozano, [...], M. Perez, R. Perona, A.G. Quiroga, C. Calés, I. Sanchez-Perez << Fewer
https://doi.org/10.1016/j.gendis.2023.02.025
Published: 27 March 2023
2023, 10 (4): 1180-1182
Downloads: 3 | Views: 128 | PDF (666.5 KB)
Open Access Rapid Communication
Mechano-sensitive TET1s inhibits endothelial athero-susceptible phenotype through regulating YAP phosphorylation
Lu Huang, Kai Qu, Caihong Wang, [...], Daoxi Lei, Wenhua Yan, Tianhan Li, Zhengjun Hou, Juhui Qiu, Guixue Wang << Fewer
https://doi.org/10.1016/j.gendis.2023.01.029
Published: 04 April 2023
2023, 10 (4): 1183-1186
Downloads: 2 | Views: 98 | PDF (1.1 MB)
Open Access Rapid Communication
Coinheritance of germline mutations in APC and MUTYH genes defines the clinical outcome of adenomatous polyposis syndromes
Giovanna Forte, Filomena Cariola, Antonia Lucia Buonadonna, [...], Anna Filomena Guglielmi, Andrea Manghisi, Katia De Marco, Valentina Grossi, Candida Fasano, Martina Lepore Signorile, Paola Sanese, Rosanna Bagnulo, Nicoletta Resta, Vittoria Disciglio, Cristiano Simone << Fewer
https://doi.org/10.1016/j.gendis.2022.11.017
Published: 27 December 2022
2023, 10 (4): 1187-1189
Downloads: 2 | Views: 89 | PDF (246.2 KB)
Open Access Rapid Communication
Development of a molecular feature-based survival prediction model of ovarian cancer using the deep neural network
Tingyuan Lang, Muyao Yang, Yunqiu Xia, [...], Jingshu Liu, Yunzhe Li, Lingling Yang, Chenxi Cui, Yunran Hu, Yang Luo, Dongling Zou, Lei Zhou, Zhou Fu, Qi Zhou << Fewer
https://doi.org/10.1016/j.gendis.2022.10.011
Published: 26 October 2022
2023, 10 (4): 1190-1193
Downloads: 2 | Views: 106 | PDF (1.4 MB)
Open Access Rapid Communication
Integrative multi-platform meta-analysis of hepatocellular carcinoma gene expression profiles for identifying prognostic and diagnostic biomarkers
Maryam Gholizadeh, Morteza Hadizadeh, Seyed Reza Mazlooman, [...], Saeid Eslami, Sadegh Raoufi, Marziye Farsimadan, Maryam Rashidifar, Marek Drozdzik, Mehrnaz Mehrabani << Fewer
https://doi.org/10.1016/j.gendis.2022.07.018
Published: 13 August 2022
2023, 10 (4): 1194-1196
Downloads: 5 | Views: 128 | PDF (961.2 KB)
Open Access Rapid Communication
A color-based FHGC approach facilities DNA-based clinical molecular diagnostics
Ruyi Zhang, Dongyang Deng, Min Ren, [...], Jiangyan He, Fang Chen, Shujuan Yan << Fewer
https://doi.org/10.1016/j.gendis.2022.07.007
Published: 05 August 2022
2023, 10 (4): 1197-1199
Downloads: 2 | Views: 96 | PDF (1 MB)
Open Access Rapid Communication
Rare variant analysis of PLXNA1 in Parkinson’s disease in the Chinese population
Chunyu Li, Ruwei Ou, Yanbing Hou, [...], Junyu Lin, Kuncheng Liu, Qianqian Wei, Xueping Chen, Wei Song, Bi Zhao, Huifang Shang << Fewer
https://doi.org/10.1016/j.gendis.2022.08.001
Published: 19 August 2022
2023, 10 (4): 1200-1202
Downloads: 3 | Views: 103 | PDF (396.1 KB)
Open Access Rapid Communication
The tRNA-derived fragment tRF-5022a positively regulates melanogenesis
Si Li, Lan Zhang, Jing Chen, [...], Ling Jiang, Chuhan Fu, Ao Huang, Xinxin Lei, Siyu Yang, Qinghai Zeng, Ke Cao << Fewer
https://doi.org/10.1016/j.gendis.2022.07.020
Published: 13 August 2022
2023, 10 (4): 1203-1205
Downloads: 3 | Views: 110 | PDF (938.6 KB)
Open Access Rapid Communication
Pan-cancer analysis of DNA methyltransferase family with potential implications in prognosis and immunology in human cancer
Jiayu Ding, Hao Shen, Dawei Wang, [...], Wenbin Kuang, Liping Wang, Xiao Wang, Peng Yang << Fewer
https://doi.org/10.1016/j.gendis.2022.07.016
Published: 10 August 2022
2023, 10 (4): 1206-1209
Downloads: 2 | Views: 121 | PDF (1.2 MB)
Open Access Rapid Communication
Super-enhancer-associated TTC8 alters the nucleocytoplasmic distribution of PHOX2B and activates MAPK signaling in neuroblastoma
Ran Zhuo, Zimu Zhang, Xinyi Guo, [...], Haibo Cao, Yanling Chen, Yanfang Tao, Randong Yang, Xiaolu Li, Jian Pan, Jian Wang << Fewer
https://doi.org/10.1016/j.gendis.2022.07.014
Published: 07 August 2022
2023, 10 (4): 1210-1213
Downloads: 2 | Views: 89 | PDF (1.2 MB)
Open Access Rapid Communication
Deletion of G protein-coupled receptor 116 enhances neutrophil function and aggravates lung injury in mice
Ting Wang, Ying Wang, Qian Xiang, [...], Shengwei Lin, Peipei Jin, Jun Wang, Na Li, Jiafeng Wang, Jinjun Bian << Fewer
https://doi.org/10.1016/j.gendis.2022.08.017
Published: 24 September 2022
2023, 10 (4): 1214-1216
Downloads: 2 | Views: 104 | PDF (1.1 MB)
Open Access Rapid Communication
Impact of the COVID-19 pandemic on lung cancer treatment and research
Shreya Kailas Lovlekar, Yihua Wang
https://doi.org/10.1016/j.gendis.2023.01.028
Published: 24 March 2023
2023, 10 (4): 1217-1219
Downloads: 2 | Views: 127 | PDF (517.6 KB)
REVIEW ARTICLES
Open Access Review Article
DEAD-box RNA helicases with special reference to p68: Unwinding their biology, versatility, and therapeutic opportunity in cancer
Shaheda Tabassum, Mrinal K. Ghosh
https://doi.org/10.1016/j.gendis.2022.02.008
Published: 21 March 2022
2023, 10 (4): 1220-1241
Downloads: 3 | Views: 142 | PDF (2.3 MB)
Open Access Review Article
Protein post-translational modification by lysine succinylation: Biochemistry, biological implications, and therapeutic opportunities
Guo Zhao, Junfeng Zhen, Xinyuan Liu, [...], Jinshuai Guo, Duanduan Li, Jianping Xie, Longxiang Xie << Fewer
https://doi.org/10.1016/j.gendis.2022.03.009
Published: 07 April 2022
2023, 10 (4): 1242-1262
Downloads: 3 | Views: 135 | PDF (2 MB)
Open Access Review Article
Is there a potential of circulating miRNAs as biomarkers in rheumatic diseases?
Klára Prajzlerová, Ladislav Šenolt, Mária Filková
https://doi.org/10.1016/j.gendis.2022.08.011
Published: 07 September 2022
2023, 10 (4): 1263-1278
Downloads: 2 | Views: 126 | PDF (680.2 KB)
Open Access Review Article
The role of circadian clocks in cancer: Mechanisms and clinical implications
Huiwen Liu, Ying Liu, Rihan Hai, [...], Weihua Liao, Xiangjian Luo << Fewer
https://doi.org/10.1016/j.gendis.2022.05.014
Published: 28 May 2022
2023, 10 (4): 1279-1290
Downloads: 7 | Views: 119 | PDF (892.2 KB)
Open Access Review Article
Wnt signaling: Essential roles in osteoblast differentiation, bone metabolism and therapeutic implications for bone and skeletal disorders
Rexhina Vlashi, Xingen Zhang, Mengrui Wu, Guiqian Chen
https://doi.org/10.1016/j.gendis.2022.07.011
Published: 06 August 2022
2023, 10 (4): 1291-1317
Downloads: 2 | Views: 112 | PDF (1.8 MB)
Open Access Review Article
Targeting PD-1/PD-L1 in cancer immunotherapy: An effective strategy for treatment of triple-negative breast cancer (TNBC) patients
Sunny Kumar, Mouli Chatterjee, Pratyasha Ghosh, [...], Kirat K. Ganguly, Malini Basu, Mrinal K. Ghosh << Fewer
https://doi.org/10.1016/j.gendis.2022.07.024
Published: 24 August 2022
2023, 10 (4): 1318-1350
Downloads: 3 | Views: 176 | PDF (3 MB)
Open Access Review Article
Long noncoding RNA (lncRNA) H19: An essential developmental regulator with expanding roles in cancer, stem cell differentiation, and metabolic diseases
Junyi Liao, Bowen Chen, Zhenglin Zhu, [...], Chengcheng Du, Shengqiang Gao, Guozhi Zhao, Piao Zhao, Yonghui Wang, Annie Wang, Zander Schwartz, Lily Song, Jeffrey Hong, William Wagstaff, Rex C. Haydon, Hue H. Luu, Jiaming Fan, Russell R. Reid, Tong-Chuan He, Lewis Shi, Ning Hu, Wei Huang << Fewer
https://doi.org/10.1016/j.gendis.2023.02.008
Published: 24 March 2023
2023, 10 (4): 1351-1366
Downloads: 2 | Views: 130 | PDF (1.3 MB)
Open Access Review Article
Cancer chemotherapy and beyond: Current status, drug candidates, associated risks and progress in targeted therapeutics
Uttpal Anand, Abhijit Dey, Arvind K. Singh Chandel, [...], Rupa Sanyal, Amarnath Mishra, Devendra Kumar Pandey, Valentina De Falco, Arun Upadhyay, Ramesh Kandimalla, Anupama Chaudhary, Jaspreet Kaur Dhanjal, Saikat Dewanjee, Jayalakshmi Vallamkondu, José M. Pérez de la Lastra << Fewer
https://doi.org/10.1016/j.gendis.2022.02.007
Published: 18 March 2022
2023, 10 (4): 1367-1401
Downloads: 5 | Views: 166 | PDF (2.5 MB)
Open Access Review Article
COVID-19 therapeutics: Clinical application of repurposed drugs and futuristic strategies for target-based drug discovery
Sunny Kumar, Malini Basu, Pratyasha Ghosh, [...], Uttam Pal, Mrinal K. Ghosh << Fewer
https://doi.org/10.1016/j.gendis.2022.12.019
Published: 07 April 2023
2023, 10 (4): 1402-1428
Downloads: 4 | Views: 148 | PDF (4.5 MB)
Open Access Review Article
Histone post-translational modification and the DNA damage response
Haoyun Song, Rong Shen, Xiangwen Liu, [...], Xuguang Yang, Kun Xie, Zhao Guo, Degui Wang << Fewer
https://doi.org/10.1016/j.gendis.2022.04.002
Published: 22 April 2022
2023, 10 (4): 1429-1444
Downloads: 2 | Views: 150 | PDF (2.1 MB)
Open Access Review Article
Cervical cancer: a tale from HPV infection to PARP inhibitors
Minakshi Mann, Vikram Pratap Singh, Lalit Kumar
https://doi.org/10.1016/j.gendis.2022.09.014
Published: 10 November 2022
2023, 10 (4): 1445-1456
Downloads: 2 | Views: 133 | PDF (1.7 MB)
Open Access Review Article
Interplays of liver fibrosis-associated microRNAs: Molecular mechanisms and implications in diagnosis and therapy
Hong Li, Tingli Liu, Yongchun Yang, [...], William C. Cho, Robin J. Flynn, Majid Fasihi Harandi, Houhui Song, Xuenong Luo, Yadong Zheng << Fewer
https://doi.org/10.1016/j.gendis.2022.08.013
Published: 05 September 2022
2023, 10 (4): 1457-1469
Downloads: 2 | Views: 126 | PDF (1.2 MB)
Open Access Review Article
Molecular basis of fluoride toxicities: Beyond benefits and implications in human disorders
Priyankar Pal, Niraj Kumar Jha, Debankur Pal, [...], Saurabh Kumar Jha, Uttpal Anand, Abilash Valsala Gopalakrishnan, Abhijit Dey, Prabir Kumar Mukhopadhyay << Fewer
https://doi.org/10.1016/j.gendis.2022.09.004
Published: 21 September 2022
2023, 10 (4): 1470-1493
Downloads: 4 | Views: 142 | PDF (4.2 MB)
Open Access Review Article
Emerging chemical engineering of exosomes as “bioscaffolds” in diagnostics and therapeutics
Jianwei Wang, Meijiao Wang, Ning Jiang, [...], Shijia Ding, Qiling Peng, Lei Zheng << Fewer
https://doi.org/10.1016/j.gendis.2022.10.020
Published: 19 November 2022
2023, 10 (4): 1494-1512
Downloads: 2 | Views: 129 | PDF (3.7 MB)
Open Access Review Article
The role of TGF-β in the tumor microenvironment of pancreatic cancer
Qiang Luo, Ziquan Hu, Hongcheng Zhao, [...], Yanmei Fan, Xiancong Tu, Yueqing Wang, Xiaowen Liu << Fewer
https://doi.org/10.1016/j.gendis.2022.10.019
Published: 19 November 2022
2023, 10 (4): 1513-1524
Downloads: 2 | Views: 123 | PDF (1 MB)
Open Access Review Article
Adiponectin and metabolic cardiovascular diseases: Therapeutic opportunities and challenges
Xiaotian Lei, Sheng Qiu, Gangyi Yang, Qinan Wu
https://doi.org/10.1016/j.gendis.2022.10.018
Published: 17 November 2022
2023, 10 (4): 1525-1536
Downloads: 3 | Views: 145 | PDF (1.8 MB)
Open Access Review Article
The multifaceted role of placental growth factor in the pathogenesis and progression of bronchial asthma and pulmonary fibrosis: Therapeutic implications
Dan Huang, Gege Liu, Zhiyi Xu, [...], Shushu Chen, Cuili Wang, Dewei Liu, Jiahao Cao, Junfen Cheng, Bin Wu, Dong Wu << Fewer
https://doi.org/10.1016/j.gendis.2022.10.017
Published: 14 November 2022
2023, 10 (4): 1537-1551
Downloads: 3 | Views: 122 | PDF (1.8 MB)
FULL LENGTH ARTICLES
Open Access Full Length Article
Protective effects of IRG1/itaconate on acute colitis through the inhibition of gasdermins-mediated pyroptosis and inflammation response
Wenchang Yang, Yaxin Wang, Tao Wang, [...], Chengguo Li, Liang Shi, Peng Zhang, Yuping Yin, Kaixiong Tao, Ruidong Li << Fewer
https://doi.org/10.1016/j.gendis.2022.05.039
Published: 20 June 2022
2023, 10 (4): 1552-1563
Downloads: 2 | Views: 117 | PDF (3.6 MB)
Open Access Full Length Article
PLSCR1 promotes apoptosis and clearance of retinal ganglion cells in glaucoma pathogenesis
Jingyi Luo, Qing Lian, Deliang Zhu, [...], Minglei Zhao, Tingfang Mei, Bizhi Shang, Zeqiu Yang, Chujun Liu, Wenchang Xu, Lan Zhou, Keling Wu, Xinqi Liu, Yuhua Lai, Fuxiang Mao, Weihua Li, Chengguo Zuo, Kang Zhang, Mingkai Lin, Yehong Zhuo, Yizhi Liu, Lin Lu, Ling Zhao << Fewer
https://doi.org/10.1016/j.gendis.2022.05.036
Published: 21 June 2022
2023, 10 (4): 1564-1581
Downloads: 3 | Views: 139 | PDF (7.1 MB)
Open Access Full Length Article
Progranulin regulation of autophagy contributes to its chondroprotective effect in osteoarthritis
Yiming Pan, Yuyou Yang, Mengtian Fan, [...], Cheng Chen, Rong Jiang, Li Liang, Menglin Xian, Biao Kuang, Nana Geng, Naibo Feng, Lin Deng, Wei Zheng, Fengmei Zhang, Xiaoli Li, Fengjin Guo << Fewer
https://doi.org/10.1016/j.gendis.2022.05.031
Published: 13 June 2022
2023, 10 (4): 1582-1595
Downloads: 2 | Views: 132 | PDF (3.3 MB)
Open Access Full Length Article
Hepatocyte nuclear factor 1A suppresses innate immune response by inducing degradation of TBK1 to inhibit steatohepatitis
Jinyong He, Cong Du, Xuyun Peng, [...], Weilong Hong, Dongbo Qiu, Xiusheng Qiu, Xingding Zhang, Yunfei Qin, Qi Zhang << Fewer
https://doi.org/10.1016/j.gendis.2022.05.029
Published: 07 June 2022
2023, 10 (4): 1596-1612
Downloads: 7 | Views: 211 | PDF (4.2 MB)
Open Access Full Length Article
Extracellular vesicles derived from human dental mesenchymal stem cells stimulated with low-intensity pulsed ultrasound alleviate inflammation-induced bone loss in a mouse model of periodontitis
Tingwei Zhang, Ziqi Chen, Mengyuan Zhu, [...], Xuan Jing, Xiaohui Xu, Xulei Yuan, Mengjiao Zhou, Yanan Zhang, Miao Lu, Duanjing Chen, Shihan Xu, Jinlin Song << Fewer
https://doi.org/10.1016/j.gendis.2022.06.009
Published: 19 July 2022
2023, 10 (4): 1613-1625
Downloads: 2 | Views: 112 | PDF (2.7 MB)
Open Access Full Length Article
Antagonizing exosomal miR-18a-5p derived from prostate cancer cells ameliorates metastasis-induced osteoblastic lesions by targeting Hist1h2bc and activating Wnt/β-catenin pathway
Fanchun Zeng, Chunrong Zhao, Rujie Wang, [...], Lingyan Ren, Hao Qiu, Zhi Zou, Haibin Ding, Zhongyi Sun, Jianmei Li, Shiwu Dong << Fewer
https://doi.org/10.1016/j.gendis.2022.06.007
Published: 30 July 2022
2023, 10 (4): 1626-1640
Downloads: 2 | Views: 140 | PDF (4.4 MB)
Open Access Full Length Article
Suppression of osteosarcoma progression by engineered lymphocyte-derived proteomes
Kexin Li, Xun Sun, Hudie Li, [...], Hailan Ma, Meng Zhou, Kazumasa Minami, Keisuke Tamari, Kazuhiko Ogawa, Pankita H. Pandya, M. Reza Saadatzadeh, Melissa A. Kacena, Karen E. Pollok, Bai-Yan Li, Hiroki Yokota << Fewer
https://doi.org/10.1016/j.gendis.2022.08.007
Published: 28 August 2022
2023, 10 (4): 1641-1656
Downloads: 4 | Views: 144 | PDF (4.5 MB)
Open Access Full Length Article
Hallmark guided identification and characterization of a novel immune-relevant signature for prognostication of recurrence in stage Ⅰ–Ⅲ lung adenocarcinoma
Yongqiang Zhang, Zhao Yang, Yuqin Tang, [...], Chengbin Guo, Danni Lin, Linling Cheng, Xun Hu, Kang Zhang, Gen Li << Fewer
https://doi.org/10.1016/j.gendis.2022.07.005
Published: 05 August 2022
2023, 10 (4): 1657-1674
Downloads: 3 | Views: 148 | PDF (5.8 MB)
Open Access Full Length Article
Single-cell transcriptome landscape and antigen receptor dynamic during SARS-CoV-2 vaccination
Xiaojian Cao, Xiaohua Chen, Yaqi Zhu, [...], Xiaojuan Gou, Keyi Yan, Bing Yang, Dong Men, Lei Liu, Yong-an Zhang, Gang Cao << Fewer
https://doi.org/10.1016/j.gendis.2022.08.020
Published: 08 September 2022
2023, 10 (4): 1675-1686
Downloads: 2 | Views: 130 | PDF (4.6 MB)
Open Access Full Length Article
Niclosamide (NA) overcomes cisplatin resistance in human ovarian cancer
Linjuan Huang, Jing Zhang, Youling Deng, [...], Hao Wang, Piao Zhao, Guozhi Zhao, Wei Zeng, Yonghui Wang, Connie Chen, William Wagstaff, Rex C. Haydon, Russell R. Reid, Tong-Chuan He, Le Shen, Hue H. Luu, Ling Zhao << Fewer
https://doi.org/10.1016/j.gendis.2022.12.005
Published: 02 January 2023
2023, 10 (4): 1687-1701
Downloads: 3 | Views: 130 | PDF (5 MB)
Open Access Full Length Article
PD-L1 expression is regulated by ATP-binding of the ERBB3 pseudokinase domain
Yamu Li, Zhonghua Liu, Yiqing Zhao, [...], Jie Yang, Tsan Sam Xiao, Ronald A. Conlon, Zhenghe Wang << Fewer
https://doi.org/10.1016/j.gendis.2022.11.003
Published: 08 December 2022
2023, 10 (4): 1702-1713
Downloads: 6 | Views: 124 | PDF (2.9 MB)
Open Access Full Length Article
Osteopontin (OPN) alleviates the progression of osteoarthritis by promoting the anabolism of chondrocytes
Wei Luo, Zili Lin, Yuhao Yuan, [...], Ziyi Wu, Wei Zhong, Qing Liu << Fewer
https://doi.org/10.1016/j.gendis.2022.08.010
Published: 01 September 2022
2023, 10 (4): 1714-1725
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