Genes & Diseases

ISSN 2352-4820 e-ISSN 2352-3042 CN 50-1221/R

Editors-in-Chief: Ailong Huang, Tong-Chuan He

Open Access

Articles & Issues

Advanced Search

Previous Issue

Previous Issue

Next Issue

All Issues

Volume 9

Issue 1, January 2022

pp.1-284 26 articles

Contents(PDF)

RAPID COMMUNICATIONS

Open Access Rapid Communication

Anti-C4d chimeric antigen receptor regulatory T cells suppressed allograft rejection in ABO-incompatible heart transplantation

Sun-Kyung Lee, Jerome Han, Honglin Piao, [...], Nara Shin, Joon Young Jang, Ji-Jing Yan, Hyori Kim, Junho Chung, Jaeseok Yang << Fewer

https://doi.org/10.1016/j.gendis.2021.07.001

Published: 28 July 2021

2022, 9 (1): 1-4

Downloads: 5 | Views: 160 |

PDF (1.1 MB)

Open Access Rapid Communication

Mediator complex subunit 12 is a gatekeeper of SARS-CoV-2 infection in breast cancer cells

Shengjie Zhang, Fabao Liu, Peter Halfmann, [...], Ryan T. Behrens, Peng Liu, Sean J. Mcilwain, Irene M. Ong, Kristine Donahue, Yidan Wang, Yoshihiro Kawaoka, Nathan Sherer, Wei Xu << Fewer

https://doi.org/10.1016/j.gendis.2021.08.001

Published: 17 August 2021

2022, 9 (1): 5-8

Downloads: 3 | Views: 150 |

PDF (1.1 MB)

Open Access Rapid Communication

Favorable prognostic role of IL-26 in HCC patients associated with JAK-STAT3-dependent autophagy

Qihong Zhao, Chen Wang, Kexin Wang, [...], Yue He, Anla Hu, Min Tang, Wanshui Yang, Jiyu Cao, Dexiang Xu, Hua Wang << Fewer

https://doi.org/10.1016/j.gendis.2021.08.002

Published: 20 August 2021

2022, 9 (1): 9-11

Downloads: 1 | Views: 148 |

PDF (1 MB)

REVIEW ARTICLES

Open Access Review Article

CCL5/CCR5 axis in human diseases and related treatments

Zhen Zeng, Tianxia Lan, Yuquan Wei, Xiawei Wei

https://doi.org/10.1016/j.gendis.2021.08.004

Published: 26 August 2021

2022, 9 (1): 12-27

Downloads: 2 | Views: 205 |

PDF (1.1 MB)

Open Access Review Article

The KiSS-1/GPR54 system: Essential roles in physiological homeostasis and cancer biology

Nisha Zhu, Mengxiang Zhao, Yuxian Song, [...], Liang Ding, Yanhong Ni << Fewer

https://doi.org/10.1016/j.gendis.2020.07.008

Published: 24 July 2020

2022, 9 (1): 28-40

Downloads: 4 | Views: 169 |

PDF (1.2 MB)

Open Access Review Article

The USP7 protein interaction network and its roles in tumorigenesis

Ahood Al-Eidan, Yihua Wang, Paul Skipp, Rob M. Ewing

https://doi.org/10.1016/j.gendis.2020.10.004

Published: 22 October 2020

2022, 9 (1): 41-50

Downloads: 3 | Views: 198 |

PDF (785.7 KB)

Open Access Review Article

Critical roles of FTO-mediated mRNA m6A demethylation in regulating adipogenesis and lipid metabolism: Implications in lipid metabolic disorders

Zhou Yang, Guang-li Yu, Xiao Zhu, [...], Tian-hong Peng, Yun-cheng Lv << Fewer

https://doi.org/10.1016/j.gendis.2021.01.005

Published: 28 January 2021

2022, 9 (1): 51-61

Downloads: 6 | Views: 188 |

PDF (1.2 MB)

Open Access Review Article

Age-related macular degeneration: Epidemiology, genetics, pathophysiology, diagnosis, and targeted therapy

Yanhui Deng, Lifeng Qiao, Mingyan Du, [...], Chao Qu, Ling Wan, Jie Li, Lulin Huang << Fewer

https://doi.org/10.1016/j.gendis.2021.02.009

Published: 27 February 2021

2022, 9 (1): 62-79

Downloads: 4 | Views: 210 |

PDF (3.2 MB)

Open Access Review Article

Pharmacological perspectives and molecular mechanisms of coumarin derivatives against virus disease

Zhoupeng Li, Dehui Kong, Yongsheng Liu, Mingkai Li

https://doi.org/10.1016/j.gendis.2021.03.007

Published: 20 April 2021

2022, 9 (1): 80-94

Downloads: 3 | Views: 196 |

PDF (1.7 MB)

Open Access Review Article

SATB2: A versatile transcriptional regulator of craniofacial and skeleton development, neurogenesis and tumorigenesis, and its applications in regenerative medicine

Xia Huang, Qiuman Chen, Wenping Luo, [...], Mikhail Pakvasa, Yuxin Zhang, Liwen Zheng, Shuang Li, Zhuohui Yang, Huan Zeng, Fang Liang, Fugui Zhang, Daniel A. Hu, Kevin H. Qin, Eric J. Wang, David S. Qin, Russell R. Reid, Tong-Chuan He, Aravind Athiviraham, Mostafa El Dafrawy, Hongmei Zhang << Fewer

https://doi.org/10.1016/j.gendis.2020.10.003

Published: 17 October 2020

2022, 9 (1): 95-107

Downloads: 1 | Views: 179 |

PDF (1.5 MB)

FULL LENGTH ARTICLES

Open Access Full Length Article

Pancreatic stromal Gremlin 1 expression during pancreatic tumorigenesis

Joy M. Davis, Binglu Cheng, Madeline M. Drake, [...], Qiang Yu, Baibing Yang, Jing Li, Chunhui Liu, Mamoun Younes, Xiurong Zhao, Jennifer M. Bailey, Qiang Shen, Tien C. Ko, Yanna Cao << Fewer

https://doi.org/10.1016/j.gendis.2020.05.001

Published: 16 May 2020

2022, 9 (1): 108-115

Downloads: 2 | Views: 180 |

PDF (2.1 MB)

Open Access Full Length Article

Transcriptomic profiling of peroxisome-related genes reveals a novel prognostic signature in hepatocellular carcinoma

Liewang Qiu, Ke Zhan, Kija Malale, [...], Xiaoling Wu, Zhechuan Mei << Fewer

https://doi.org/10.1016/j.gendis.2020.04.010

Published: 21 April 2020

2022, 9 (1): 116-127

Downloads: 5 | Views: 182 |

PDF (4.4 MB)

Open Access Full Length Article

Osteopontin inhibits osteoarthritis progression via the OPN/CD44/PI3K signal axis

Qing Liu, Hao Zeng, Yuhao Yuan, [...], Zhiwei Wang, Ziyi Wu, Wei Luo << Fewer

https://doi.org/10.1016/j.gendis.2020.06.006

Published: 27 June 2020

2022, 9 (1): 128-139

Downloads: 7 | Views: 217 |

PDF (5.6 MB)

Open Access Full Length Article

Lysyl oxidase inhibition enhances browning of white adipose tissue and adaptive thermogenesis

Chun Xing, Duo Jiang, Yang Liu, [...], Qiqun Tang, Haiyan Huang << Fewer

https://doi.org/10.1016/j.gendis.2020.10.001

Published: 10 October 2020

2022, 9 (1): 140-150

Downloads: 3 | Views: 149 |

PDF (2.5 MB)

Open Access Full Length Article

LPCAT1 functions as a novel prognostic molecular marker in hepatocellular carcinoma

Hongbin Zhang, Ke Xu, Qin Xiang, [...], Lijuan Zhao, Benxu Tan, Ping Ju, Xiufu Lan, Yi Liu, Jian Zhang, Zheng Fu, Chao Li, Jinzhi Wang, Jixiang Song, Yun Xiao, Zhaobo Cheng, Yan Wang, Shu Zhang, Tingxiu Xiang << Fewer

https://doi.org/10.1016/j.gendis.2020.07.007

Published: 21 July 2020

2022, 9 (1): 151-164

Downloads: 3 | Views: 190 |

PDF (3.6 MB)

Open Access Full Length Article

Transient expression of inactive RB in mesenchymal stem cells impairs their adipogenic potential and is associated with hypermethylation of the PPARγ2 promoter

Mikhail Baryshev, Nikolai Petrov, Vladimir Ryabov, Boris Popov

https://doi.org/10.1016/j.gendis.2020.11.001

Published: 07 November 2020

2022, 9 (1): 165-175

Downloads: 2 | Views: 164 |

PDF (2.1 MB)

Open Access Full Length Article

A heterozygous N-terminal truncation mutation of NFKBIA results in an impaired NF-κB dependent inflammatory response

Wen Wen, Li Wang, Mengyue Deng, [...], Yue Li, Xuemei Tang, Huawei Mao, Xiaodong Zhao << Fewer

https://doi.org/10.1016/j.gendis.2021.03.005

Published: 03 April 2021

2022, 9 (1): 176-186

Downloads: 3 | Views: 152 |

PDF (1.4 MB)

Open Access Full Length Article

Tsc2 mutation induces renal tubular cell nonautonomous disease

Prashant Kumar, Fahad Zadjali, Ying Yao, [...], Daniel Johnson, Brian Siroky, Aristotelis Astrinidis, Peter Vogel, Kenneth W. Gross, John J. Bissler << Fewer

https://doi.org/10.1016/j.gendis.2021.03.010

Published: 27 April 2021

2022, 9 (1): 187-200

Downloads: 1 | Views: 180 |

PDF (3 MB)

Open Access Full Length Article

Comparison of hepatic gene expression profiles between three mouse models of Nonalcoholic Fatty Liver Disease

Liping Xiang, Yang Jiao, Yiling Qian, [...], Yao Li, Fei Mao, Yan Lu << Fewer

https://doi.org/10.1016/j.gendis.2021.02.008

Published: 27 February 2021

2022, 9 (1): 201-215

Downloads: 2 | Views: 180 |

PDF (3.5 MB)

Open Access Full Length Article

Identification of cross-reactive CD8⁺ T cell receptors with high functional avidity to a SARS-CoV-2 immunodominant epitope and its natural mutant variants

Chao Hu, Meiying Shen, Xiaojian Han, [...], Qian Chen, Luo Li, Siyin Chen, Jing Zhang, Fengxia Gao, Wang Wang, Yingming Wang, Tingting Li, Shenglong Li, Jingjing Huang, Jianwei Wang, Ju Zhu, Dan Chen, Qingchen Wu, Kun Tao, Da Pang, Aishun Jin << Fewer

https://doi.org/10.1016/j.gendis.2021.05.006

Published: 29 June 2021

2022, 9 (1): 216-229

Downloads: 1 | Views: 188 |

PDF (2 MB)

Open Access Full Length Article

PRR11 induces filopodia formation and promotes cell motility via recruiting ARP2/3 complex in non-small cell lung cancer cells

Zhili Wei, Ru Wang, Xun Yin, [...], lian Zhang, Yunlong Lei, Ying Zhang, Yi Li, Jiaqian Wu, Youquan Bu, Guoxiang Jin, Chundong Zhang << Fewer

https://doi.org/10.1016/j.gendis.2021.02.012

Published: 02 March 2021

2022, 9 (1): 230-244

Downloads: 42 | Views: 241 |

PDF (5.6 MB)

Open Access Full Length Article

The role of distinct co-mutation patterns with TP53 mutation in immunotherapy for NSCLC

Shuhang Wang, Miaomiao Jiang, Zuozhen Yang, [...], Xiaoyun Huang, Ning Li << Fewer

https://doi.org/10.1016/j.gendis.2020.04.001

Published: 09 April 2020

2022, 9 (1): 245-251

Downloads: 5 | Views: 207 |

PDF (476.3 KB)

Open Access Full Length Article

PTEN and AKT/GSK-3β/CRMP-2 signaling pathway are involved in neuronal apoptosis and axonal injury in early brain injury after SAH in rats

Hong Chen, Chao Zhou, Jianfeng Zheng, [...], Zhaosi Zhang, Yongbing Deng, Chongjie Cheng, Zongduo Guo, Gang Huo, Cheng Yin, Xiaochuan Sun << Fewer

https://doi.org/10.1016/j.gendis.2020.05.002

Published: 18 June 2020

2022, 9 (1): 252-267

Downloads: 1 | Views: 172 |

PDF (7.3 MB)

Open Access Full Length Article

Mettl5 mediated 18S rRNA N6-methyladenosine (m⁶A) modification controls stem cell fate determination and neural function

Lu Wang, Yu Liang, Rongzhi Lin, [...], Qiuchan Xiong, Peng Yu, Jieyi Ma, Maosheng Cheng, Hui Han, Xiaochen Wang, Ganping Wang, Fengyin Liang, Zhong Pei, Demeng Chen, Quan Yuan, Yi-Zhou Jiang, Shuibin Lin << Fewer

https://doi.org/10.1016/j.gendis.2020.07.004

Published: 17 July 2020

2022, 9 (1): 268-274

Downloads: 1 | Views: 181 |

PDF (1.4 MB)

Open Access Full Length Article

A peptide-based assay discriminates individual antibody response to SARS-CoV-2

Immacolata Polvere, Serena Voccola, Gaetano Cardinale, [...], Maurizio Fumi, Francesca Aquila, Alfredina Parrella, Jessica Raffaella Madera, Romania Stilo, Pasquale Vito, Tiziana Zotti << Fewer

https://doi.org/10.1016/j.gendis.2021.01.008

Published: 05 February 2021

2022, 9 (1): 275-281

Downloads: 2 | Views: 170 |

PDF (1.3 MB)

CORRECTION

Erratum

Corrigendum to “Identification and characterization of the cellular subclones that contribute to the pathogenesis of mantle cell lymphoma” [Genes Dis 6(4) 2019 407–418]

Junling Tang, Li Zhang, Tiejun Zhou, [...], Zhiwei Sun, Liangsheng Kong, Li Jing, Hongyun Xing, Hongyan Wu, Yongli Liu, Shixia Zhou, Jingyuan Li, Mei Chen, Fang Xu, Jirui Tang, Tao Ma, Min Hu, Dan Liu, Jing Guo, Xiaofeng Zhu, Yan Chen, Ting Ye, Jianyu Wang, Xiaoming Li, H. Rosie Xing << Fewer

https://doi.org/10.1016/j.gendis.2021.06.001

Published: 22 June 2021

2022, 9 (1): 282-284

Downloads: 5 | Views: 186 |

PDF (1.3 MB)