Food & Medicine Homology Resources is an international, peer-reviewed, interdisciplinary, open-access journal supporting strategies related to broad agriculture, comprehensive food systems, comprehensive stewardship, outer-space utilization, and holistic health. The journal is dedicated to advancing integrative research across multiple disciplines, including food science, traditional Chinese medicine, medical sciences, nutrition, artificial intelligence, bioinformatics, synthetic biology, aerospace medicine, deep-sea biology and polar ecology. It publishes cutting-edge original research and high-quality review articles, reporting advances in the discovery of new food-medicine homologous resources, validation of their nutritional and health functions, safety and toxicological evaluations, quality assessment, and interdisciplinary studies on the high-value and comprehensive utilization of these resources.
Food & Medicine Homology Resources focuses on the discovery of animal, plant, and microbial resources with health-promoting functions. Utilizing advanced analytical instruments alongside well-designed in vitro and in vivo experimental evaluation systems, the journal aims to provide robust scientific evidence supporting the safe dietary and medicinal use of these resources. It strives to advance frontier research, guide the development of multidisciplinary sciences, and promote industrial development and progress. Articles published in the journal must demonstrate innovation, significant impact, and high academic quality.
Scope of Food & Medicine Homology Resources:
Resource Discovery and Synthetic Biology: Studies on the classification, identification, and origin traceability of food-medicine homologous resources; applications of genomics, metabolomics, and bioinformatics in resource exploration. Discovery and mechanistic studies of key enzymes involved in the biosynthesis of functional components; total synthesis of functional components and construction of engineering microorganisms; large-scale fermentation processes and biotransformation technologies.
Comprehensive Utilization and Sustainable Development of Resources: High-value conversion and recycling of by-products derived from food-medicine homologous resources; regeneration of waste resources and engineering technologies for edible transformation and resource safety and toxicological evaluations.
Interdisciplinary Integration and Innovative Applications: Development and utilization of specialized equipment and processes for resource applications across food, pharmaceuticals, clinical nutrition, and fine chemical fields; application of emerging technologies in resource development, including advanced methods for efficient detection and characterization of functional components, design and fabrication of functional materials, and the development of nano-delivery systems and formulations.
Specialized field:
Space Health: Covering resources from special habitats across all spatial domains and health in extreme environments, with a focus on medicinal and edible homologous resources derived from special habitats across all spatial domains, and encompassing resource exploration in outer space (low Earth orbit and deep space) and Earth's extreme environments (deep sea, high-altitude plateaus, polar regions, high-temperature hot springs, and arid zones); functional and safety assessments against space-associated stressors (radiation, hypoxia, microgravity, bone loss, and immune dysregulation); closed-loop cultivation and resource recycling in isolated and confined environments; and translational applications for human spaceflight, deep-space exploration, and extreme-environment missions on Earth.
Discovery and resource utilization of novel functional substance entities: This research area focuses on emerging substance entities, including supramolecular assemblies, extracellular vesicle-like structures, formula-derived assemblies, and traditional Chinese medicine-derived carbon dots, with emphasis on their structural characteristics, formation and assembly mechanisms, in vivo disposition, mechanisms of action, and pharmacological and functional evaluation.
AI-Powered Food-Medicine Homology and Resource Utilization: Covering the transformative integration of artificial intelligence (AI) into food-medicine homology research, a paradigm shift from experience-driven to data-driven approaches and from qualitative description to quantitative prediction; Encompassing the construction of novel datasets for systematic investigations across traditional Chinese medicine, medicine-food homology resources, functional foods, nutrition, and dietary intervention strategies; Development of computational algorithms and AI-powered tools for TCM knowledge mining, dietary pattern discovery, personalized nutrition recommendation, and clinical decision support; Integration of the multi-level, multi-dimensional of heterogeneous data for material basis evaluation, disease prevention, nutritional outcome quantification, and individualized response prediction.
Edible Engineering Innovative Technologies: Preservation of traditional Chinese medicine processing technologies while balancing toxicity reduction, efficacy enhancement, and edible quality. This includes AI technologies that provide a new paradigm for processing research, and organoid-on-a-chip systems for safety and activity evaluation. It covers AI-powered analysis of the dynamic chemical evolution during processing and identification of toxicity/efficacy biomarkers; AI-driven discovery of molecular mechanisms underlying processing-induced toxicity reduction and efficacy enhancement; intelligent optimization and process control of processing technologies; and edible-oriented processing and dual-objective optimization of medicinal and edible homologous substances.
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