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Review | Publishing Language: Chinese | Open Access

Research Progress in Taste Mechanism and Debittering Technologies of Bitter Peptides

Ran TU1,2 ( )Yan LI1
School of Food Science and Engineering, Chongqing Technology and Business University, Chongqing 400067, China
Key Laboratory of Natural Medicine Research of Chongqing Education Commission, Chongqing 400067, China
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Abstract

Bitter peptides are generated during enzymatic protein hydrolysis. Their bitterness mainly originates from hydrophobic amino acids, which significantly affects the flavor quality of foods. Although these peptides exhibit certain biological activities, their intense bitter taste greatly limits the application of protein hydrolysates in food products. This review systematically summarizes the formation pathways of bitter peptides, their dual effects on food sensory quality, and the methods currently used for their separation and identification. It further explores the structural basis and taste mechanism of bitter peptides, while providing a comparative analysis of various debittering methods, including selective separation, masking, and structural modification. This review aims to offer theoretical insights and technical references for the utilization of bitter peptides.

CLC number: TS201.2 Document code: A Article ID: 1002-6630(2026)05-0393-11

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Food Science
Pages 393-403

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Cite this article:
TU R, LI Y. Research Progress in Taste Mechanism and Debittering Technologies of Bitter Peptides. Food Science, 2026, 47(5): 393-403. https://doi.org/10.7506/spkx1002-6630-20250806-041

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Received: 06 August 2025
Published: 15 March 2026
© Beijing Academy of Food Sciences 2026.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).