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Publishing Language: Chinese | Open Access

Recent Advances in Food-Derived Antioxidant Peptides and Their Role in Improving Cardiovascular Health

Lei HUANG1 Lihua HAN2Kai WANG1 ( )Yang LIU1Bo PANG1Wenlong MA1Boxing YIN3Xia CHEN1Yujun HUANG1Ruixia GU1
Key Laboratory of Probiotics and Deep Processing of Dairy Products, College of Food Science and Engineering, Yangzhou University, Yangzhou 225127, China
Jiangsu College of Tourism, Yangzhou 225000, China
Jiangsu Provincial Research Center for Dairy Bioengineering Technology, Yangzhou 225004, China
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Abstract

Cardiovascular diseases (CVDs) have emerged as a critical global public health challenge, with their pathological progression being closely linked to oxidative stress in cardiovascular cells. Although pharmacological interventions exhibit efficacy in CVD management, most of them have adverse effects. In recent years, bioactive peptides derived from dietary proteins have gained significant attention due to their potent antioxidant properties and excellent safety profiles, positioning them as promising food-derived functional agents for preventing and ameliorating CVDs. This review systematically summarizes recent advances in the development of food-derived antioxidant peptides, encompassing their production strategies, structure-activity relationships, absorption and metabolism. Particular emphasis is placed on their effects and mechanisms of action in improving cardiovascular health, aiming to provide a theoretical foundation for advancing research on CVD interventions and fostering innovation in peptide-based functional food products.

CLC number: TS201.4 Document code: A Article ID: 1002-6630(2026)01-0377-15

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Food Science
Pages 377-391

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Cite this article:
HUANG L, HAN L, WANG K, et al. Recent Advances in Food-Derived Antioxidant Peptides and Their Role in Improving Cardiovascular Health. Food Science, 2026, 47(1): 377-391. https://doi.org/10.7506/spkx1002-6630-20250526-168

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Received: 26 May 2025
Published: 15 January 2026
© Beijing Academy of Food Sciences 2026.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).