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Review | Publishing Language: Chinese | Open Access

Research Progress on Digestion, Absorption and Nutritional Functions of Milk Osteopontin

Juan ZHANG1 , Xi CHEN1, Yuting LI2,3, Xujin YANG2,3, Ailiang CHEN1 ( )
Institute of Quality Standard and Testing Technology for Agro-products, Chinese Academy of Agricultural Sciences, Beijing 100081, China
College of Food Science and Engineering, Inner Mongolia Agricultural University, Hohhot 010018, China
Yang Xujin Innovation Studio, Inner Mongolia Agricultural University, Hohhot 010018, China
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Abstract

Milk osteopontin, a multifunctional phosphorylated glycoprotein derived from milk, plays significant roles in immune regulation, as well as promoting brain development and cognitive function, intestinal health and bone health, and it is recognized as a novel ingredient for infant formula and related food products. With the aim of providing a reference for the development and utilization of milk osteopontin, this article systematically elaborates on recent advancements in its structural characteristics, digestion, absorption and nutritional functions, and discusses its future application prospects and research directions as a novel food ingredient.

Keywords

milk osteopontinstructural characteristicsdigestion and absorptionnutritional functions
CLC number: TS252.1 Document code: A Article ID: 1002-6630(2025)17-0345-13

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Food Science
Volume 46 Issue 17,
September 2025
Pages 345-357
DOI: 10.7506/spkx1002-6630-20250317-132

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Cite this article:
ZHANG J, CHEN X, LI Y, et al. Research Progress on Digestion, Absorption and Nutritional Functions of Milk Osteopontin. Food Science, 2025, 46(17): 345-357. https://doi.org/10.7506/spkx1002-6630-20250317-132

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Received: 17 March 2025
Published: 15 September 2025
© Beijing Academy of Food Sciences 2025.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).