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Review | Publishing Language: Chinese | Open Access

Research Progress on the Application and Mechanism of Medium-Chain Fatty Acids in Adjuvant Therapy of Diseases

Xiwen JIA1 Jiajie XU2Xueyan LIANG1Hui ZHANG1Hao LIN1Kaili DING1Yinghui HE1Luoyang LIU1Lujia HAN1Weihua XIAO1 ( )
College of Engineering, China Agricultural University, Beijing 100083, China
School of Marine Sciences, Ningbo University, Ningbo 315211, China
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Abstract

As people’s consumption levels and health awareness have risen, the consumer demand for functional foods is steadily increasing. Medium-chain fatty acids (MCFAs), an important class of dietary fatty acids, have been regarded as high-value functional foods due to their unique transportation system and the fact that they can be metabolized rapidly in the body while producing high energy. Beginning with an overview of the types and structures of MCFAs, this paper goes on to elaborate the metabolic pathway of MCFAs in the human body and then summarize recent research on MCFAs in the adjuvant treatment of different diseases. This article focuses on the positive role of MCFAs in the adjuvant treatment of Alzheimer’s disease, epilepsy, cancer, diabetes, obesity, and other diseases, and expounds their action mechanism. Finally, an outlook on the future development of MCFAs is given. Overall, this review provides a theoretical basis for promoting the application of MCFAs in the fields of food and medicine.

CLC number: TS229 Document code: A Article ID: 1002-6630(2024)04-0344-08

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Food Science
Pages 344-351

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Cite this article:
JIA X, XU J, LIANG X, et al. Research Progress on the Application and Mechanism of Medium-Chain Fatty Acids in Adjuvant Therapy of Diseases. Food Science, 2024, 45(4): 344-351. https://doi.org/10.7506/spkx1002-6630-20230303-034

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Received: 03 March 2023
Published: 25 February 2024
© Beijing Academy of Food Sciences 2024.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).