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Review | Publishing Language: Chinese | Open Access

Research Progress in Heterologous Expression, Fermentation and Application of Microbial Transglutaminase

Wenhui YAN1,2 , Xinjie SUN1,2, Xiangheng XI1,2, Chenying WANG1,3 ( ), Xidong REN1,2 ( )
State Key Laboratory of Biobased Material and Green Papermaking, Qilu University of Technology, Shandong Academy of Sciences, Jinan 250353, China
Shandong Provincial Key Laboratory of Microbial Engineering, Qilu University of Technology, Shandong Academy of Sciences, Jinan 250353, China
School of Food Science and Engineering, Qilu University of Technology, Shandong Academy of Sciences, Jinan 250353, China
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Abstract

Transglutaminase (TG) is a widely used enzyme with excellent protein cross-linking capacity. TG is commonly found in plants, animals and microorganisms, and microbial TG (mTG) is widely used in industrial production and application because of its good enzymatic properties. This paper describes the physicochemical properties and activation mechanism of mTG, and summarizes recent progress in mTG production by wild and different genetically engineered strains. Meanwhile, the application and potential of mTG in various industrial fields are reviewed. This review is expected to provide a reference and new ideas for research on the potential of mTG for industrial production and application.

Keywords

transglutaminaseactivation mechanismfermentationheterologous expressionapplication
CLC number: TS201.3 Document code: A Article ID: 1002-6630(2023)23-0223-08

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Food Science
Volume 44 Issue 23,
December 2023
Pages 223-230
DOI: 10.7506/spkx1002-6630-20221125-293

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Cite this article:
YAN W, SUN X, XI X, et al. Research Progress in Heterologous Expression, Fermentation and Application of Microbial Transglutaminase. Food Science, 2023, 44(23): 223-230. https://doi.org/10.7506/spkx1002-6630-20221125-293

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Received: 25 November 2022
Published: 15 December 2023
© Beijing Academy of Food Sciences 2023.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).