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Research Article | Open Access

Antibacterial Activity of Cu Nanoparticles against E. coli, Staphylococcus aureus and Pseudomonas aeruginosa

Lalit Yadav1Ravi Mani Tripathi1Ram Prasad2Ramesh Namdeo Pudake1Jagjiwan Mittal1( )
Amity Institute of Nanoatechnology, Amity University, Noida-201301, Uttar Pradesh, India
Amity Institute of Microbial Technology, Amity University, Noida-201301, Uttar Pradesh, India
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Abstract

Copper nanoparticles (CuNPs) were synthesized under ambient temperature by wet chemical method and evaluated their antibacterial activity by the means of well diffusion method. In this study, we have analyzed the effect of NaBH4 concentration on the synthesis of CuNPs. Surface plasmon resonance (SPR) was occurred at 575 nm. Scanning electron microscopy micrographs shows CuNPs have spherical morphology with size range of 20-40 nm. Dynamic light scattering (DLS) showed the particles size increases with the concentration of reducing agent NaBH4. As prepared, CuNPs, demonstrated antibacterial activity against E. coli, Staphylococcus aureus and Pseudomonas aeruginosa. The potential mechanism of antibacterial activity was discussed with diagrammatic representation.

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Nano Biomedicine and Engineering
Pages 9-14
Cite this article:
Yadav L, Tripathi RM, Prasad R, et al. Antibacterial Activity of Cu Nanoparticles against E. coli, Staphylococcus aureus and Pseudomonas aeruginosa. Nano Biomedicine and Engineering, 2017, 9(1): 9-14. https://doi.org/10.5101/nbe.v9i1.p9-14

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Received: 10 February 2017
Accepted: 13 March 2017
Published: 17 March 2017
© 2017 Lalit Yadav, Ravi Mani Tripathi, Ram Prasad, Ramesh Namdeo Pudake, and Jagjiwan Mittal.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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