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Review | Open Access

New Developments of Gastric Cancer Biomarker Research

Hualin Fu1,2( )
Institute of Nano Biomedicine and Engineering, Key Laboratory for Thin Film and Microfabrication of the Ministry of Education, Department of Instrument Science and Engineering, School of Electronic Information and Electrical Engineering, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai, 200240, China
National Center for Translational Medicine, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai, 200240, China
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Abstract

Gastric cancer is a deadly disease with high incidence and mortality rate in China. Early detection and treatment of gastric cancer showed significantly better 5-year survival rate. Conventional screening methods of gastric cancer include barium meal or endoscopic screening. There is a great need to find new biomarkers of gastric cancer for simpler, faster, and non-invasive screening of gastric cancer. A large array of molecules such as protein markers, metabolite markers, RNA markers, breath organic molecules have been identified as potential markers of gastric screening. Among them, pepsinogens and gastrin-17 have been applied in large scale of population screening. New species of metabolite markers, microRNA markers and breath molecules may further enhance the simplicity, sensitivity and specificity of gastric cancer screening.

Keywords

Gastric cancerBiomarkerProteinRNAVolatile organic compoundMetabolite

References

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Nano Biomedicine and Engineering
Volume 8 Issue 4,
December 2016
Pages 268-273
DOI: 10.5101/nbe.v8i4.p268-273

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Cite this article:
Fu H. New Developments of Gastric Cancer Biomarker Research. Nano Biomedicine and Engineering, 2016, 8(4): 268-273. https://doi.org/10.5101/nbe.v8i4.p268-273

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Received: 27 September 2016
Accepted: 18 November 2016
Published: 06 December 2016
© 2016 Hualin Fu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.