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Aloe Vera-conjugated Ag nanoparticles (AgNPs@AV hybrids) are synthesized in large quantities by reducing silver nitrate with Aloe Vera pulp extract at room temperature. TEM image reveals that these NPs are predominantly spherical with an average of 25 nm in diameter. The crystal structure of AgNPs@AV is determined by XRD. The cytotoxicity of AgNPs@AV hybrids is detected by carrying out the cell viability measurement on Human Dermal Fibroblasts (HDF) cells, the results show that no obvious cytotoxicity is observed. Compared with Vera gel and Ag NPs (washed from Vera gel) alone, AgNPs@AV hybrids possess more excellent antibacterial activity on E. coli even at very low concentration.

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Publication history

Received: 15 November 2010
Accepted: 06 December 2010
Published: 16 December 2010
Issue date: December 2010

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© 2010 Y. Zhang et al.

Acknowledgements

This work is supported by the National Key Basic Research Program (973 Project) (2010CB933901), National 863 Hi-tech Project (2007AA022004, Important National Science & Technology Specific Projects (2009ZX10004-311), National Natural Scientific Fund (No. 20771075 and No. 20803040), Special project for nanotechnology from Shanghai (No. 1052nm04100), New Century Excellent Talent of Ministry of Education of China (NCET-08-0350) and Shanghai Science and Technology Fund (10XD1406100).

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This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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