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Article | Open Access

Electrochemical Property and Cell Toxicity of Gold Electrode Modified by Monolayer PAMAM Encapsulated Gold Nanorods

Xueqing Zhang, Bifeng Pan, Kan Wang, Jing Ruan, Chenchen Bao, Hao Yang, Rong He, Daxiang Cui( )
Department of Bio-Nano-Science and Engineering, National Key Laboratory of Nano/Micro Fabrication Technology, Key Laboratory for Thin Film and Microfabrication of Ministry of Education, Institute of Micro-Nano Science and Technology, Shanghai Jiao Tong University, Shanghai 200240, China

Note: Xueqing Zhang and Bifeng Pan are equally contributed to this work

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Abstract

Herein we exploit the molecular engineering capability to immobilize monolayer of polyamidoamine dendrimer on gold electrode, which exhibit enhanced charge transfer and biocompatibility. Polyamidoamine (PAMAM generation 5.0) dendrimers were used as template/stabilizers for gold nanoparticle growth, with Au@PAMAM nanoparticles serving as surface modifier to produce monolayer film. TEM, UV-vis spectroscopy, and AFM were used to characterize the formation of monolayer Au@PAMAM on gold surface. The cyclic voltammetry (CV) and Impedance measurements of Au@PAMAM modified gold electrodes demonstrate electrochemistry properties of modified electrode. Furthermore, Au@PAMAM coating can greatly increased the biocompatibility of gold electrode as determined by cell growth curves

Keywords

MonolayerGold electrodeCyclic voltammetryBiocompatibility

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Nano Biomedicine and Engineering
Volume 2 Issue 3,
September 2010
Pages 182-188
DOI: 10.5101/nbe.v2i3.p182-188

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Cite this article:
Zhang X, Pan B, Wang K, et al. Electrochemical Property and Cell Toxicity of Gold Electrode Modified by Monolayer PAMAM Encapsulated Gold Nanorods. Nano Biomedicine and Engineering, 2010, 2(3): 182-188. https://doi.org/10.5101/nbe.v2i3.p182-188

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Received: 16 July 2010
Accepted: 22 September 2010
Published: 04 October 2010
© 2010 X. Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.