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Research Article | Open Access

Facile Green Synthesis of Ag/AgCl Nanocomposite Using Durian Shell Extract and its Activity Against Methicillin-Resistant Staphylococcus Aureus

Thi Anh Thu Nguyen1, Thi My Thao Nguyen1, Thi Thanh Le Trinh1, Phung Anh Nguyen2, Van Minh Nguyen3, Nhat Linh Duong3, Trung Dang-Bao4( ), Nguyen Tri2,3( )
School of Applied Chemistry, Tra Vinh University, Tra Vinh City, Vietnam
Institute of Chemical Technology, Vietnam Academy of Science and Technology, Ho Chi Minh City, Vietnam
Faculty of Biotechnology, Ho Chi Minh City Open University, Ho Chi Minh City, Vietnam
Faculty of Chemical Engineering, Ho Chi Minh City University of Technology, VNU-HCM, Ho Chi Minh City, Vietnam
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Abstract

The green synthesis of Ag/AgCl nanocomposite using the durian shell extract was carried out under the sunlight illumination at room temperature, showing the face-centered cubic crystalline structures of both Ag and AgCl with nanosizes in the range of 15–25 nm. The high negative potential value of the Ag/AgCl solution (–21.1 mV) established the high dispersion of Ag/AgCl, long-term stability, and good colloidal nature. The antibacterial activity of Ag/AgCl nanocomposite against methicillin-resistant Staphylococcus aureus (MRSA) bacteria was highly appreciated with average inhibition zone diameter of 12.0 mm, minimum inhibitory concentration of 8.27 mg/L, and minimum bactericidal concentration of 66.1 mg/L. The present work designed a cost-effective, convenient, eco-friendly protocol to synthesize Ag/AgCl nanocomposite and its efficient antibacterial activity against MRSA was evidenced as well.

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Nano Biomedicine and Engineering
Pages 225-235

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Cite this article:
Nguyen TAT, Nguyen TMT, Trinh TTL, et al. Facile Green Synthesis of Ag/AgCl Nanocomposite Using Durian Shell Extract and its Activity Against Methicillin-Resistant Staphylococcus Aureus. Nano Biomedicine and Engineering, 2022, 14(3): 225-235. https://doi.org/10.5101/nbe.v14i3.p225-235

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Received: 25 September 2021
Revised: 21 September 2022
Accepted: 14 November 2022
Published: 30 November 2022
© Thi Anh Thu Nguyen, Thi My Thao Nguyen, Thi Thanh Le Trinh, Phung Anh Nguyen, Van Minh Nguyen, Nhat Linh Duong, Trung Dang-Bao, Nguyen Tri.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.