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Advances in multidisciplinary research have paved the way for the development of nano-technological applications for utilization across a diversity of fields, including infectious diseases, agriculture, and the environment. Nanoparticles can be used for targeting and can play a vital role in the health sector. Using chemical methods, nanoparticles have been produced for a very long time, but due to the release of the harmful chemicals during their production and higher cost associated with the methodology, alternative methods such as green syntheses have been introduced. The green synthesis method is preferred over chemical methods attributed to the absence of fumes in green synthesis as compared to the chemical method. Nowadays, the antibiotic resistant microbes and the development of superbugs are a major problem in health sector, so as there are certain studies about the antimicrobial activities of metallic NPs, which can provide an alternative approach against these resistant microbes. The understanding about these NPs in bio-medical applications is not well studied. This systematic review will help the scientific community to understand the actual potential of these NPs as an effective antimicrobial and anticancer agent.


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Green Synthesis of Metallic Nano-Particles and Their Potential in Bio-Medical Applications

Show Author's information Tayyab Shafiq1( )Mohammad Uzair2Muhammad Junaid Iqbal1Mohsin Zafar1Syed Jawad Hussain2Syed Alasar Ali Shah1
Department of Biosciences, COMSATS University, 44000, Islamabad, Pakistan
Department of Biological Sciences, International Islamic University, 44000, Islamabad, Pakistan

Abstract

Advances in multidisciplinary research have paved the way for the development of nano-technological applications for utilization across a diversity of fields, including infectious diseases, agriculture, and the environment. Nanoparticles can be used for targeting and can play a vital role in the health sector. Using chemical methods, nanoparticles have been produced for a very long time, but due to the release of the harmful chemicals during their production and higher cost associated with the methodology, alternative methods such as green syntheses have been introduced. The green synthesis method is preferred over chemical methods attributed to the absence of fumes in green synthesis as compared to the chemical method. Nowadays, the antibiotic resistant microbes and the development of superbugs are a major problem in health sector, so as there are certain studies about the antimicrobial activities of metallic NPs, which can provide an alternative approach against these resistant microbes. The understanding about these NPs in bio-medical applications is not well studied. This systematic review will help the scientific community to understand the actual potential of these NPs as an effective antimicrobial and anticancer agent.

Keywords: Characterization, Nanoparticles, Anti-cancer, Green synthesis, Metallic NPs, Anti-microbial

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Received: 27 August 2020
Accepted: 22 April 2021
Published: 27 May 2021
Issue date: June 2021

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© Tayyab Shafiq, Mohammad Uzair, Muhammad Junaid Iqbal, Mohsin Zafar, Syed Jawad Hussain, and Syed Alasar Ali Shah.

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Authors gratefully acknowledge all the respective departments for their favors

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