Effect of Viscosity and Density of Substance on Dielectric Properties of Medicinal Compounds in Solution

Jinan Fadhil Mahdi; Ansari Abdul Jaleel Abdul Haque; Mazahar Ahmed Nazeeruddin Farooqui; Yusuf Hanif Shaikh

doi:10.5101/nbe.v12i4.p351-357

Nano Biomedicine and Engineering 2020, 12(4): 351-357 https://doi.org/10.5101/nbe.v12i4.p351-357

Research Article |

Open Access | Issue | Published: 03 December 2020

Effect of Viscosity and Density of Substance on Dielectric Properties of Medicinal Compounds in Solution

Show Author's Information Hide Author's Information Jinan Fadhil Mahdi^¹(

), Ansari Abdul Jaleel Abdul Haque^², Mazahar Ahmed Nazeeruddin Farooqui^³, Yusuf Hanif Shaikh^⁴

College of Electrical Engineering Techniques, Middle Technical University, Ministry of Higher Education and Scientific Research, Iraq

Department of Physics and Electronics, Maulana Azad College of Arts, Science and Commerce, Aurangabad, Maharashtra, India

Department of Chemistry, Maulana Azad College of Arts, Science and Commerce, Aurangabad, Maharashtra, India

Department of Physics and Electronics, Shivaji College, Kannad, Aurangabad, Maharashtra, India

Keywords:

Dielectric constant, Microwave bench, Magnetic stirrer, Ostwald's viscometer, Specific gravity bottle, Relaxation time, Debye model

Cite this article:

Mahdi JF, Haque AAJA, Farooqui MAN, et al. Effect of Viscosity and Density of Substance on Dielectric Properties of Medicinal Compounds in Solution. Nano Biomedicine and Engineering, 2020, 12(4): 351-357. https://doi.org/10.5101/nbe.v12i4.p351-357

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Abstract

Complex permittivity in terms of dielectric constant (ε') and dielectric loss (ε") of medicinal compound paracetamol in dimethyl sulfoxide (DMSO) solvent was determined with different weight fractions at microwave frequency 9.85 GHz at constant temperature 27 ℃. The information on dielectric properties is related to the properties of the substance for preparation of granules while making dosage forms like tablets and capsules. Refractive index (nD), dielectricconstant (ε') and dielectric loss (ε") were used for the measurement of relaxation time (τ). The viscosity (η) and density of paracetamol in DMSO were determined using a conventional Ostwald's viscometer and specific gravity bottle respectively. The aim of the present work was to study the dielectric properties of the drugs and attempted to determine their correlations with density and viscosity to understand the behavior of the dielectric properties under different conditions like a concentration in solution. It was observed that there was a strong correlation of dielectric properties like dielectric constant, dielectric loss and dielectric relaxation time with viscosity and density. The absolute values of correlation coefficient (R) were in the range of 0.946 to 0.987 for paracetamol-DMSO system, indicating a strong correlation.

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Effect of Viscosity and Density of Substance on Dielectric Properties of Medicinal Compounds in Solution

Show Author's information Hide Author's Information Jinan Fadhil Mahdi^¹(

), Ansari Abdul Jaleel Abdul Haque^², Mazahar Ahmed Nazeeruddin Farooqui^³, Yusuf Hanif Shaikh^⁴

College of Electrical Engineering Techniques, Middle Technical University, Ministry of Higher Education and Scientific Research, Iraq

Department of Physics and Electronics, Maulana Azad College of Arts, Science and Commerce, Aurangabad, Maharashtra, India

Department of Chemistry, Maulana Azad College of Arts, Science and Commerce, Aurangabad, Maharashtra, India

Department of Physics and Electronics, Shivaji College, Kannad, Aurangabad, Maharashtra, India

Abstract

Keywords: Dielectric constant, Microwave bench, Magnetic stirrer, Ostwald's viscometer, Specific gravity bottle, Relaxation time, Debye model

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Publication history

Received: 17 May 2020

Accepted: 11 September 2020

Published: 03 December 2020

Issue date: December 2020

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This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.