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Nano Biomedicine and Engineering 2020, 12(3): 214-226 https://doi.org/10.5101/nbe.v12i3.p214-226
Research Article | Open Access | Issue | Published: 11 August 2020

Synthesis of Bio-Inspired Silver Nanoparticles by Ripe and Unripe Fruit Extract of Tinospora cordifolia and Its Antioxidant, Antibacterial and Catalytic Studies

Show Author's Information Praveena Kanagala1,†,  Susmila Aparna Gaddam2,†( ),  Priyanka Gunji1,  Venkata Subbaiah Kotakadi1,†( ),  Chandra Mouli Kalla3,  Vijaya Tartte3,  Divi Venkata Ramana Sai Gopal1
DST-PURSE Centre, Sri Venkateswara University, Tirupati, Andhra Pradesh, India
Department of Virology, Sri Venkateswara University, Tirupati, Andhra Pradesh, India
Department of Botany, Sri Venkateswara University, Tirupati, Andhra Pradesh, India

† Authors contributed equally to the work.

Keywords:
Antimicrobial activity, Spectral characterization, Tinospora cordifolia, Fruit mediated green synthesis, Catalytic activity studies
Cite this article:
Kanagala P, Gaddam SA, Gunji P, et al. Synthesis of Bio-Inspired Silver Nanoparticles by Ripe and Unripe Fruit Extract of Tinospora cordifolia and Its Antioxidant, Antibacterial and Catalytic Studies. Nano Biomedicine and Engineering, 2020, 12(3): 214-226. https://doi.org/10.5101/nbe.v12i3.p214-226
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Abstract Full text About this article

Green synthesis of silver nanoparticles (Ag NPs) by both ripe and unripe fruit extract was carried out by an important medicinal plant Tinospora cordifolia. The ripe and unripe fruit extract mediated bio-inspired Ag NPs showed surface plasmon resonance (SPR) band at 431 and 421 nm respectively and confirmed the formation of Tc-Ag NPs. The functional groups of bioactive components of ripe and unripe fruits were identified which reduced silver nitrate to silver ions by Fourier-transform infrared spectroscopy (FTIR). The size distribution of biosynthesized Tc-Ag NPs of ripe and unripe was determined by particle size analyzer which revealed that the Z average of Tc-Ag NPs was around 30-35 nm ± 1 nm and 30-35.8 nm ± 1 nm with an Z average of 25.9 and 28.5 nm respectively. Tc-Ag NPs exhibited stability due to its high negative zeta potential for both ripe and unripe fruit extract mediated Tc-Ag NPs as of -27.2 and -24.6 mV. Tc-Ag NPs were used to evaluate the antibacterial, antioxidant and catalytic activities. The Tc-Ag NPs revealed good antimicrobial activity. Antibiotic erythromycin was used as a standard in the present study. The Tc-Ag NPs of both ripe and unrippen fruits disclosed greater free radical scavenging efficacy which proved to be potent antioxidant agents and also exhibited potential catalytic activity by converting 4 nitro-phenol to 4 amino phenols at rapid pace. It was concluded that the Tc-Ag NPs synthesized by ripe and unripe fruits almost showed similar results, and so both of them proved to have excellent multifunctional biomedical properties.


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About this article

Synthesis of Bio-Inspired Silver Nanoparticles by Ripe and Unripe Fruit Extract of Tinospora cordifolia and Its Antioxidant, Antibacterial and Catalytic Studies

Show Author's information Praveena Kanagala1,†, Susmila Aparna Gaddam2,†( ), Priyanka Gunji1, Venkata Subbaiah Kotakadi1,†( ), Chandra Mouli Kalla3, Vijaya Tartte3, Divi Venkata Ramana Sai Gopal1
DST-PURSE Centre, Sri Venkateswara University, Tirupati, Andhra Pradesh, India
Department of Virology, Sri Venkateswara University, Tirupati, Andhra Pradesh, India
Department of Botany, Sri Venkateswara University, Tirupati, Andhra Pradesh, India

† Authors contributed equally to the work.

Abstract

Green synthesis of silver nanoparticles (Ag NPs) by both ripe and unripe fruit extract was carried out by an important medicinal plant Tinospora cordifolia. The ripe and unripe fruit extract mediated bio-inspired Ag NPs showed surface plasmon resonance (SPR) band at 431 and 421 nm respectively and confirmed the formation of Tc-Ag NPs. The functional groups of bioactive components of ripe and unripe fruits were identified which reduced silver nitrate to silver ions by Fourier-transform infrared spectroscopy (FTIR). The size distribution of biosynthesized Tc-Ag NPs of ripe and unripe was determined by particle size analyzer which revealed that the Z average of Tc-Ag NPs was around 30-35 nm ± 1 nm and 30-35.8 nm ± 1 nm with an Z average of 25.9 and 28.5 nm respectively. Tc-Ag NPs exhibited stability due to its high negative zeta potential for both ripe and unripe fruit extract mediated Tc-Ag NPs as of -27.2 and -24.6 mV. Tc-Ag NPs were used to evaluate the antibacterial, antioxidant and catalytic activities. The Tc-Ag NPs revealed good antimicrobial activity. Antibiotic erythromycin was used as a standard in the present study. The Tc-Ag NPs of both ripe and unrippen fruits disclosed greater free radical scavenging efficacy which proved to be potent antioxidant agents and also exhibited potential catalytic activity by converting 4 nitro-phenol to 4 amino phenols at rapid pace. It was concluded that the Tc-Ag NPs synthesized by ripe and unripe fruits almost showed similar results, and so both of them proved to have excellent multifunctional biomedical properties.

Keywords: Antimicrobial activity, Spectral characterization, Tinospora cordifolia, Fruit mediated green synthesis, Catalytic activity studies

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Publication history
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Acknowledgements
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Publication history

Received: 13 November 2019
Accepted: 21 July 2020
Published: 11 August 2020
Issue date: September 2020

Copyright

© Praveena Kanagala, Susmila Aparna Gaddam, Priyanka Gunji, Venkata Subbaiah Kotakadi, Chandra Mouli Kalla, Vijaya Tartte, and Divi Venkata Ramana Sai Gopal.

Acknowledgements

Acknowledgements

The authors were grateful to DST-PURSE Programme, sponsored by DST New Delhi, for providing fellowship to work under this program at Sri Venkateswara University, Tirupati.

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This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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