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Nano Biomedicine and Engineering 2020, 12(1): 104-113 https://doi.org/10.5101/nbe.v12i1.p104-113
Research Article | Open Access | Issue | Published: 25 March 2020

Biological and Photocatalytic Activity of Silver Nanoparticle Synthesized from Ehretia laevis Roxb. Leaves Extract

Show Author's Information Sudipata Panja1,  Indranil Choudhuri1,  Kalyani Khanra1,  Bikas Ranjan Pati2,  Nandan Bhattacharyya1( )
Department of Biotechnology, Panskura Banamali College, P.O. - Panskura R.S., Dist. - Purba Medinipur, West Bengal, PIN 721152, India
Department of Microbiology, Vidyasagar University, Rangamati, Medinipur, West Bengal, PIN 721102, India
Keywords:
Photocatalytic activity, Cytotoxicity, Silver nanoparticles, Antimicrobial activity, Ehretia laevis Roxb.
Cite this article:
Panja S, Choudhuri I, Khanra K, et al. Biological and Photocatalytic Activity of Silver Nanoparticle Synthesized from Ehretia laevis Roxb. Leaves Extract. Nano Biomedicine and Engineering, 2020, 12(1): 104-113. https://doi.org/10.5101/nbe.v12i1.p104-113
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Abstract Full text About this article

Silver nanoparticles were synthesized from Ehretia laevis Roxb. leaf extract by one-step green synthesis method. The nanoparticles were crystalline in nature, spherical shaped with 25 to 35 nm diameter. The aim of this study was the synthesis and characterization of silver nanoparticles from Ehretia laevis Roxb., and the evaluation of their antimicrobial, anticancer, larvicidal and methylene blue dye degradation efficiency. The nanoparticles showed antimicrobial, larvicidal and cytotoxic activity. At a concentration of 25 μg/mL, it killed 70 ± 10.24% of Culex quinquefasciatus larvae after 72 h treatment. The median lethal concentration of the nanoparticles against HeLa, human cervical cancer cells, and MCF-7 human breast cancer cells, were calculated to 12.7 μg/mL and 14.5 μg/mL, respectively. The synthesized nanoparticles degraded Congo red ~ 85% within 8 h at a concentration of 200 μg/mL. Possible application of the synthesized nanoparticles are water purifying agent in presence of sunlight.


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Biological and Photocatalytic Activity of Silver Nanoparticle Synthesized from Ehretia laevis Roxb. Leaves Extract

Show Author's information Sudipata Panja1, Indranil Choudhuri1, Kalyani Khanra1, Bikas Ranjan Pati2, Nandan Bhattacharyya1( )
Department of Biotechnology, Panskura Banamali College, P.O. - Panskura R.S., Dist. - Purba Medinipur, West Bengal, PIN 721152, India
Department of Microbiology, Vidyasagar University, Rangamati, Medinipur, West Bengal, PIN 721102, India

Abstract

Silver nanoparticles were synthesized from Ehretia laevis Roxb. leaf extract by one-step green synthesis method. The nanoparticles were crystalline in nature, spherical shaped with 25 to 35 nm diameter. The aim of this study was the synthesis and characterization of silver nanoparticles from Ehretia laevis Roxb., and the evaluation of their antimicrobial, anticancer, larvicidal and methylene blue dye degradation efficiency. The nanoparticles showed antimicrobial, larvicidal and cytotoxic activity. At a concentration of 25 μg/mL, it killed 70 ± 10.24% of Culex quinquefasciatus larvae after 72 h treatment. The median lethal concentration of the nanoparticles against HeLa, human cervical cancer cells, and MCF-7 human breast cancer cells, were calculated to 12.7 μg/mL and 14.5 μg/mL, respectively. The synthesized nanoparticles degraded Congo red ~ 85% within 8 h at a concentration of 200 μg/mL. Possible application of the synthesized nanoparticles are water purifying agent in presence of sunlight.

Keywords: Photocatalytic activity, Cytotoxicity, Silver nanoparticles, Antimicrobial activity, Ehretia laevis Roxb.

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Publication history
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Publication history

Received: 07 January 2020
Accepted: 25 March 2020
Published: 25 March 2020
Issue date: March 2020

Copyright

© Sudipata Panja, Indranil Choudhuri, Kalyani Khanra, BikasRanjan Pati, and Nandan Bhattacharyya.

Acknowledgements

Acknowledgements

Author is grateful to DBT-BOOST (Govt. of West Bengal) and DST-FIST (Govt. of India) for instrumentation support.

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This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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