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This paper introduced an efficient method to obtain the solution of linear and nonlinear weakly singular kernel fractional integro-differential equations (WSKFIDEs). It used Riemann-Liouville fractional integration (R-LFI) to remove singularities and approximated the regularized problem with a combined approach using the generalized fractional step-Mittag-Leffler function (GFSMLF) and operational integral fractional Mittag matrix (OIFMM) method. The resulting algebraic equations were turned into an optimization problem. We also proved the method's accuracy in approximating any function, as well as its fractional differentiation and integration within WSKFIDEs. The proposed method was performed on some attractive examples in order to show how their solutions behave at various values of the fractional order
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