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Research Article | Open Access

Dynamics and stability analysis of nonlinear DNA molecules: Insights from the Peyrard-Bishop model

Mostafa M. A. Khater1,2,3( )Mohammed Zakarya4Kottakkaran Sooppy Nisar5Abdel-Haleem Abdel-Aty6
School of Medical Informatics and Engineering, Xuzhou Medical University, 209 Tongshan Road, 221004, Xuzhou, Jiangsu Province, PR China
Institute of Digital Economy, Ugra State University, Khanty-Mansiysk, Russia
Department of Basic Sciences, High Institute for Engineering and Technology Al Obour, Cairo 11828, Egypt
Department of Mathematics, College of Science, King Khalid University, P.O. Box 9004, Abha 61413, Saudi Arabia
Department of Mathematics, College of Science and Humanities in Alkharj, Prince Sattam Bin Abdulaziz University, Alkharj 11942, Saudi Arabia
Department of Physics, College of Sciences, University of Bisha, Bisha 61922, Saudi Arabi
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Abstract

This study explores the nonlinear Peyrard-Bishop DNA dynamic model, a nonlinear evolution equation that describes the behavior of DNA molecules by considering hydrogen bonds between base pairs and stacking interactions between adjacent base pairs. The primary objective is to derive analytical solutions to this model using the Khater Ⅲ and improved Kudryashov methods. Subsequently, the stability of these solutions is analyzed through Hamiltonian system characterization. The Peyrard-Bishop model is pivotal in biophysics, offering insights into the dynamics of DNA molecules and their responses to external forces. By employing these analytical techniques and stability analysis, this research aims to enhance the understanding of DNA dynamics and its implications in fields such as drug design, gene therapy, and molecular biology. The novelty of this work lies in the application of the Khater Ⅲ and an enhanced Kudryashov methods to the Peyrard-Bishop model, along with a comprehensive stability investigation using Hamiltonian system characterization, providing new perspectives on DNA molecule dynamics within the scope of nonlinear dynamics and biophysics.

CLC number: 35C08, 35Q05, 92C40, 70H06

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AIMS Mathematics
Pages 23449-23467

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Cite this article:
Khater MMA, Zakarya M, Nisar KS, et al. Dynamics and stability analysis of nonlinear DNA molecules: Insights from the Peyrard-Bishop model. AIMS Mathematics, 2024, 9(9): 23449-23467. https://doi.org/10.3934/math.20241140

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Received: 30 January 2024
Revised: 18 June 2024
Accepted: 05 July 2024
Published: 15 September 2024
©2024 the Author(s), licensee AIMS Press.

This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0)