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Research Article | Open Access

Acute lymphoblastic leukemia detection using ensemble features from multiple deep CNN models

Ahmed Abul Hasanaath1Abdul Sami Mohammed2Ghazanfar Latif1( )Sherif E. Abdelhamid3Jaafar Alghazo4Ahmed Abul Hussain5
Department of Computer Science, Prince Mohammad Bin Fahd University, Al-Khobar 31952, Saudi Arabia
Department of Computer Engineering, Prince Mohammad Bin Fahd University, Al-Khobar 31952, Saudi Arabia
Department of Computer and Information Sciences, Virginia Military Institute, Lexington, VA 24450, USA
Artificial Intelligence Research Initiative, College of Engineering and Mines, University of North Dakota Grand Forks, ND 58202, USA
Department of Electrical Engineering, Prince Mohammad Bin Fahd University, Al-Khobar 31952, Saudi Arabia
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Abstract

We presented a methodology for detecting acute lymphoblastic leukemia (ALL) based on image data. The approach involves two stages: Feature extraction and classification. Three state-of-the-art transfer learning models, InceptionResnetV2, Densenet121, and VGG16, were utilized to extract features from the images. The extracted features were then processed through a Global Average Pooling layer and concatenated into a flattened tensor. A linear support vector machine (SVM) classifier was trained and tested on the resulting feature set. Performance evaluation was conducted using metrics such as precision, accuracy, recall, and F-measure. The experimental results demonstrated the efficacy of the proposed approach, with the highest accuracy achieved at 91.63% when merging features from VGG16, InceptionResNetV2, and DenseNet121. We contributed to the field by offering a robust methodology for accurate classification and highlighted the potential of transfer learning models in medical image analysis. The findings provided valuable insights for developing automated systems for the early detection and diagnosis of leukemia. Future research can explore the application of this approach to larger datasets and extend it to other types of cancer classification tasks.

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Electronic Research Archive
Pages 2407-2423

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Cite this article:
Hasanaath AA, Mohammed AS, Latif G, et al. Acute lymphoblastic leukemia detection using ensemble features from multiple deep CNN models. Electronic Research Archive, 2024, 32(4): 2407-2423. https://doi.org/10.3934/era.2024110

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Received: 07 December 2023
Revised: 22 February 2024
Accepted: 01 March 2024
Published: 26 March 2024
©2024 the Author(s), licensee AIMS Press.

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0)