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Glomus tumor is a benign, subcutaneous neoplasm that typically arises in regions abundant in glomus bodies, manifesting as a painful nodule. Currently, perineal glomus tumors are rarely reported in the literature. Herein, we present a unique case of glomus tumor originating in the perineal region. Ultrasound examination revealed a heterogeneous mass within the subcutaneous soft tissue layer of the vulva, featuring a distinct boundary and peripheral blood flow signals. The ultrasound contrast imaging of this mass demonstrated rapid peripheral ring enhancement during the arterial phase, followed by a gradual inward perfusion from the periphery towards the center of the nodule-like or branching-like structure, exhibiting concentric enhancement. The internal portion of the nodule showed low enhancement, which progressively diminished during the venous and delayed phases. Subsequently, an ultrasound-guided biopsy confirmed the diagnosis of glomus tumor, and the patient underwent successful surgical treatment.
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