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Review Article | Open Access

Artificial Empathy in Therapy and Healthcare: Advancements in Interpersonal Interaction Technologies

Tianyu Jia1,Feiyu Pan2,Xingchen Yang1,3Linhong Ji2Dario Farina1( )Chong Li4( )
Department of Bioengineering, Imperial College London, London W12 0BZ, UK
Department of Mechanical Engineering, Tsinghua University, Beijing 100084, China
School of Automation, Southeast University, Nanjing 210096, China
School of Clinical Medicine (BTCH), Tsinghua Medicine, Tsinghua University, Beijing 100084, China

†These authors contributed equally to this work.

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Abstract

The healthcare sector is challenged by critical workforce shortages, and this is causing an urgent need for innovative technologies to support or augment human roles. Although much of the research effort has focused on support and training of functional tasks, the emotional impacts that humans bring to the loop have often been overlooked. This gap is particularly pressing in healthcare and therapy, where empathy and emotional support are central to patient well-being. Unlike machines, humans possess a unique capacity for empathy, connecting emotionally with others and providing the essential support that fosters healing. Bridging this gap requires integrating affective elements, such as empathy, into therapeutic systems, which is the key to improving their effectiveness. This review explores groundbreaking techniques that integrate interpersonal interactions within therapy and healthcare, focusing on multiplayer games that strengthen real-time social connections, alongside social robots and virtual agents designed to simulate human-like affective interactions. Using artificial intelligence, these technologies aim to replicate complex human dynamics and foster artificial empathy, thus revolutionizing how we deliver care and support.

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Cyborg and Bionic Systems
Article number: 0473

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Review Status: {{reviewData.commendedNum}} Commended , {{reviewData.revisionRequiredNum}} Revision Required , {{reviewData.notCommendedNum}} Not Commended Under Peer Review

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Cite this article:
Jia T, Pan F, Yang X, et al. Artificial Empathy in Therapy and Healthcare: Advancements in Interpersonal Interaction Technologies. Cyborg and Bionic Systems, 2025, 6: 0473. https://doi.org/10.34133/cbsystems.0473

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Received: 30 June 2025
Revised: 09 November 2025
Accepted: 13 November 2025
Published: 16 December 2025
© 2025 Tianyu Jia et al. Exclusive licensee Beijing Institute of Technology Press. No claim to original U.S. Government Works.

Distributed under a Creative Commons Attribution License (CC BY 4.0).