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Article | Open Access

Predictive and Global Effect of Active Smoker in Asthma Dynamics with Caputo Fractional Derivative

Muhammad Farman1,2,3( )Noreen Asghar4Muhammad Umer Saleem4Kottakkaran Sooppy Nisar5,6Kamyar Hosseini1,2,7Mohamed Hafez8,9
Faculty of Arts and Sciences, Department of Mathematics, Near East University, TRNC, Mersin 10, Nicosia, 99138, Turkey
Research Center of Applied Mathematics, Khazar University, Baku, AZ-1096, Azerbaijan
Jadara University Research Center, Jadara University, Irbid, 21110, Jordan
Department of Mathematics, University of Education, Lahore, 54600, Pakistan
Department of Mathematics, College of Science and Humanities in Al Kharj, Prince Sattam bin Abdulaziz University, Al Kharj, 16277, Saudi Arabia
Hourani Center for Applied Scientific Research, Al-Ahliyya Amman University, Amman, 19328, Jordan
Faculty of Engineering and Natural Sciences, Istanbul Okan University, Istanbul, 34959, Turkey
Faculty of Engineering and Quantity Surveying, INTI International University Colleges, Nilai, 71800, Malaysia
Faculty of Mangement, Shinawatra University, Pathum Thani, 12000, Thailand
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Abstract

Smoking is harmful to the lungs and has numerous effects on our bodies. This leads to decreased lung function, which increases the lungs’ susceptibility to asthma triggers. In this paper, we develop a new fractional-order model and investigate the impact of smoking on the progression of asthma by using the Caputo operator to analyze different factors. Using the Banach contraction principle, the existence and uniqueness of solutions are established, and the positivity and boundedness of the model are proved. The model further incorporates different stages of smoking to account for incubation periods and other latent effects, enhancing the accuracy of system dynamics. Within this Fractional operator framework, key analyses are performed, including the identification of equilibrium points, computation of the basic reproduction number, sensitivity analysis, and assessment of local and global stability with the Lyapunov function. Additionally, chaos stability employing linear response regulation is implemented mathematically, and the effect of the compartment shows through simulations. A numerical iterative method employing Newton polynomial interpolation is used to illustrate the effectiveness of the suggested model, and numerical simulations reveal its enhanced efficiency at various fractional orders. The fractional-order framework offers a more realistic representation than classical integer-order models.

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Computer Modeling in Engineering & Sciences
Pages 721-751

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Cite this article:
Farman M, Asghar N, Saleem MU, et al. Predictive and Global Effect of Active Smoker in Asthma Dynamics with Caputo Fractional Derivative. Computer Modeling in Engineering & Sciences, 2025, 145(1): 721-751. https://doi.org/10.32604/cmes.2025.069541

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Received: 25 June 2025
Accepted: 03 September 2025
Published: 30 October 2025
© The Author 2024.

This work is licensed under a Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.