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Article | Open Access

MMIF: Multimodal Medical Image Fusion Network Based on Multi-Scale Hybrid Attention

Jianjun Liu1Yang Li2( )Xiaoting Sun3( )Xiaohui Wang1Hanjiang Luo2
School of Information Science and Engineering, Qingdao Huanghai University, Qingdao, 266427, China
College of Computer Science and Engineering, Shandong University of Science and Technology, Qingdao, 266590, China
Department of Computer Science and Engineering, Tongji University, Shanghai, 201804, China
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Abstract

Multimodal image fusion plays an important role in image analysis and applications. Multimodal medical image fusion helps to combine contrast features from two or more input imaging modalities to represent fused information in a single image. One of the critical clinical applications of medical image fusion is to fuse anatomical and functional modalities for rapid diagnosis of malignant tissues. This paper proposes a multimodal medical image fusion network (MMIF-Net) based on multiscale hybrid attention. The method first decomposes the original image to obtain the low-rank and significant parts. Then, to utilize the features at different scales, we add a multiscale mechanism that uses three filters of different sizes to extract the features in the encoded network. Also, a hybrid attention module is introduced to obtain more image details. Finally, the fused images are reconstructed by decoding the network. We conducted experiments with clinical images from brain computed tomography/magnetic resonance. The experimental results show that the multimodal medical image fusion network method based on multiscale hybrid attention works better than other advanced fusion methods.

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Computers, Materials & Continua
Pages 3551-3568

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Cite this article:
Liu J, Li Y, Sun X, et al. MMIF: Multimodal Medical Image Fusion Network Based on Multi-Scale Hybrid Attention. Computers, Materials & Continua, 2025, 85(2): 3551-3568. https://doi.org/10.32604/cmc.2025.066864

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Received: 18 April 2025
Accepted: 22 July 2025
Published: 23 September 2025
© The Author 2024.

This work is licensed under a Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.