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Nanocellulose (NC) has attracted much interest in the tissue engineering (TE) field because of its properties including biocompatibility, renewability, non-toxicity, functionality, and excellent mechanical performance. This review mainly focused on the advanced applications of NC-based composites in hard TE including cartilage TE, bone TE, and dental TE, illustrated the processing methods for synthesizing scaffolds including electrospinning, freeze-drying, and 3D printing, reviewed the current status of hard TE, and presented perspective on the future of TE technology.
Financial support was provided by the special fund for Independent Innovation and Industry Development in the Core Area in Haidian District of Beijing (255-kjc-020).
This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)