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Research Article | Open Access

Towards intelligent health monitoring: A CNN-driven ultrasensitive wearable pressure sensor featuring a bio-inspired dual-layer microstructure

Feng Qin1,2,§Wenqiu Liu1,2,§Shiwei Xu1,2Zhongyong Mo1,2Mufan Zhang1,2Hua Yu1,2 ( )
Key Laboratory of Optoelectronic Technology & Systems Ministry of Education, Chongqing University, Chongqing 400044, China
College of Optoelectronic Engineering, Chongqing University, Chongqing 400044, China

§ Feng Qin and Wenqiu Liu contributed equally to this work.

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Abstract

The growing need for health monitoring, intelligent recognition, and safety assurance has driven significant interest in wearable sensing technologies. Owing to their compact size, wearability, and real-time monitoring capability, wearable sensors are increasingly used in physiological signal detection, intelligent recognition systems, and human–machine interfaces. In this work, we present a novel wearable flexible pressure sensor (WFPS) inspired by the neural tactile sensing mechanism of human skin. The sensor features a bio-inspired dual-layer microstructure design, which enhances its performance compared to conventional single-layer architectures. Specifically, the dual-layer WFPS exhibits a 57% improvement in output performance, with a sensitivity of 6.13 V/kPa—a 48% increase over single-layer devices. It reliably detects subtle pressure variations down to 1.4 Pa, shows a fast response time of 6 ms, and maintains stable operation over 2500 loading–unloading cycles. These superior characteristics enable the WFPS to monitor diverse physiological signals such as carotid pulse, laryngeal vibration, and limb movement. Furthermore, we demonstrate its utility in intelligent recognition systems through a convolutional neural network (CNN)-based handwritten digit recognition platform. Using sensor data acquired via a signal collection system, the platform achieves a recognition accuracy of 98.3% across ten digit classes. Additionally, a driver fatigue monitoring system integrating the WFPS with a hybrid CNN-LSTM algorithm is developed, enabling real-time fatigue detection with an accuracy of 96.7%. The promising performance of the WFPS in health monitoring and intelligent recognition underscores its potential for advancing future wearable technologies and smart sensor systems.

Graphical Abstract

We present a bio-inspired wearable flexible pressure sensor with a dual-ayer microstructure for high performance health monitoring and intelligent recognition, enabling accurate handwritten digit identification and real-time driver fatigue detection.

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Nano Research
Article number: 94908626

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Cite this article:
Qin F, Liu W, Xu S, et al. Towards intelligent health monitoring: A CNN-driven ultrasensitive wearable pressure sensor featuring a bio-inspired dual-layer microstructure. Nano Research, 2026, 19(6): 94908626. https://doi.org/10.26599/NR.2026.94908626
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Received: 14 January 2026
Revised: 10 February 2026
Accepted: 09 March 2026
Published: 19 May 2026
© The Author(s) 2026. Published by Tsinghua University Press.

This is an open access article under the terms of the Creative Commons Attribution 4.0 International License (CC BY 4.0, https://creativecommons.org/licenses/by/4.0/).