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Research Article | Open Access

Highly portable electrochemical oxygen removal device for microenvironmental low-oxygen control

Xin Wang1Xingen Lin1Wanyu Shen1Yimin Li1Yi Tan1Zihan Wang1Peng Jiang1Song Gong3 ( )Kong Chen1,2 ( )Yu Zhang1,2 ( )Yuen Wu1,2 ( )
Department of Endocrinology, Institute of Endocrine and Metabolic Diseases, The First Affiliated Hospital of University of Science and Technology of China (USTC), Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, China
Deep Space Exploration Laboratory, University of Science and Technology of China, Hefei 230026, China
Division of Endocrinology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan 430030, China
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Graphical Abstract

We have designed a novel electrochemically-based oxygen removal device, by using a sacrificial anode to self-power the cathodic oxygen reduction reaction. This effective oxygen removal device holds potential applications in fields such as biological sciences and anaerobic fermentation.

Abstract

Low-oxygen (O2) environments are essential in various research and application fields, yet traditional methods like nitrogen flushing or chemical O2 absorbers face challenges in high equipment cost and low controllability. This study introduces a novel electrochemical oxygen removal (EOR) controller, offering a lightweight, low-cost, and precise low-O2 control solution. The self-powered EOR controller uses a sacrificial anode to drive the cathodic oxygen reduction reaction (ORR), efficiently consuming environmental O2 to reduce its level, thus eliminating the requirements of external gas or power sources. By integrating a single-atom ORR catalyst and flexible design, the device achieves a substantial reduction in weight and cost. The incorporation of electronic components for the EOR controller, including a switch for reaching targeted O2 concentration and a fixed resistor for O2 removal rate regulation, enables multi-dimensional O2 removal control. The system also realizes the O2 concentration estimation in real-time with ±1% accuracy (within the 21%–1% range) by calculating electron transfers. The EOR controller’s effectiveness is validated in plant hypoxia stress experiments, demonstrating precise O2 level adjustments and its potential across various applications requiring controlled hypoxic conditions.

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Nano Research
Article number: 94907179
Cite this article:
Wang X, Lin X, Shen W, et al. Highly portable electrochemical oxygen removal device for microenvironmental low-oxygen control. Nano Research, 2025, 18(2): 94907179. https://doi.org/10.26599/NR.2025.94907179
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Received: 29 October 2024
Revised: 10 December 2024
Accepted: 10 December 2024
Published: 15 January 2025
© The Author(s) 2025. Published by Tsinghua University Press.

This is an open access article under the terms of the Creative Commons Attribution 4.0 International License (CC BY 4.0, https://creativecommons.org/licenses/by/4.0/).

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