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Research Article | Open Access

Super-self-assembly extraction from natural herbs

Jiawei Xiang1,2,§Yuan Meng1,2,§Mingyuan Zhao1,2Zhongxian Li1Qiang Zhang3Ning Wang4Zhuo Ao1 ( )Dong Han1,2 ( )
CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Beijing 100190, China
University of Chinese Academy of Sciences, Beijing 100049, China
Hebei Key Lab of Nano-biotechnology, Hebei Key Lab of Applied Chemistry, Yanshan University, Qinhuangdao 066004, China
Guang’anmen Hospital of the China Academy of Chinese Medical Sciences, Beijing 100053, China

§ Jiawei Xiang and Yuan Meng contributed equally to this work.

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Abstract

Life systems are complex systems, and the self-assembly behaviour represents the transition from disorder to order and serves as a concrete indicator and starting point for understanding complex systems. Super-self-assembly behaviour was observed in the decoctions of various natural herbs, and this behaviour was characterized by multistep and multilevel assembly processes. The super-self-assemblies were multilevel particles resulting from inorganic–organic assembly, specifically observed as composite spheres, cubes, and tetragonal bipyramids. The preparation process was environmentally friendly and safe, and the resulting super-self-assemblies were regular in shape and rich in variety; this process has numerous possibilities for development and application in medicine and materials research.

Graphical Abstract

A new assembly pattern has been discovered in herbal decoctions, through simply applying freezing or ion addition results in the formation of super-self-assemblies with diverse morphologies and forms. The process is eco-friendly, simple, universal, reproducible, and stable.

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Nano Research
Article number: 94907094

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Cite this article:
Xiang J, Meng Y, Zhao M, et al. Super-self-assembly extraction from natural herbs. Nano Research, 2025, 18(2): 94907094. https://doi.org/10.26599/NR.2025.94907094
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Received: 30 August 2024
Revised: 22 October 2024
Accepted: 23 October 2024
Published: 03 January 2025
© The Author(s) 2025. Published by Tsinghua University Press.

This is an open access article under the terms of the Creative Commons Attribution 4.0 International License (CC BY 4.0, https://creativecommons.org/licenses/by/4.0/).