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Nano Biomedicine and Engineering 2023, 15(4): 425-435 https://doi.org/10.26599/NBE.2023.9290039
Review | Open Access | Issue | Published: 07 November 2023

Nanoparticles-assisted Wound Healing: A Review

Show Author's Information Sarah Habeeb Hamed1,  Ebaa Adnan Azooz2( ),  Emad Abbas Jaffar Al-Mulla3( )
The Gifted Students` School in Najaf, the General Directorate of Education Al-Najaf, Ministry of Education, Iraq
Medical Laboratory Technology Department, College of Medical Technology, the Islamic University, Najaf, Iraq
College of Health and Medical Techniques, Al-Furat Al-Awsat Technical University, An-Najaf, Iraq
Keywords:
gold nanoparticles (Au NPs), zinc oxide nanoparticles (ZnO NPs), wounds caring, sliver nanoparticle (Ag NPs)
Cite this article:
Hamed SH, Azooz EA, Al-Mulla EAJ. Nanoparticles-assisted Wound Healing: A Review. Nano Biomedicine and Engineering, 2023, 15(4): 425-435. https://doi.org/10.26599/NBE.2023.9290039
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Abstract Full text About this article

Poor wound treatment impacts millions of humans worldwide, increasing deaths and costs. Wounds have three key complications: (a) a lack of an adequate environment for cell migration, proliferation, and angiogenesis; (b) microbial infection; and (c) unstable and prolonged inflammation.Regrettably, contemporary therapeutic treatments have not entirely tackled these basic difficulties and thus have insufficient medical accomplishment. The incorporation of the extraordinary capabilities of nanomaterials in wound healing has achieved major successes over the years. Nanomaterials can promote a variety of cellular and molecular processes that assist in the wound microenvironment through antibacterial, anti-inflammatory, and angiogenic activities, potentially shifting the surroundings from nonhealing to healing. The current review focuses on novel techniques, with a particular focus on recent revolutionary wound healing and infection control tactics based on nanomaterials, such as nanoparticles, nanocomposites, and scaffolds, which are discussed in depth. Furthermore, the effectiveness of nanoparticles as carriers for therapeutic compounds in wound-healing applications has been investigated which provide researchers an up-to-date sources on the use of nanomaterials and their creative ways that can improve wound-healing uses.


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About this article

Nanoparticles-assisted Wound Healing: A Review

Show Author's information Sarah Habeeb Hamed1, Ebaa Adnan Azooz2( ), Emad Abbas Jaffar Al-Mulla3( )
The Gifted Students` School in Najaf, the General Directorate of Education Al-Najaf, Ministry of Education, Iraq
Medical Laboratory Technology Department, College of Medical Technology, the Islamic University, Najaf, Iraq
College of Health and Medical Techniques, Al-Furat Al-Awsat Technical University, An-Najaf, Iraq

Abstract

Poor wound treatment impacts millions of humans worldwide, increasing deaths and costs. Wounds have three key complications: (a) a lack of an adequate environment for cell migration, proliferation, and angiogenesis; (b) microbial infection; and (c) unstable and prolonged inflammation.Regrettably, contemporary therapeutic treatments have not entirely tackled these basic difficulties and thus have insufficient medical accomplishment. The incorporation of the extraordinary capabilities of nanomaterials in wound healing has achieved major successes over the years. Nanomaterials can promote a variety of cellular and molecular processes that assist in the wound microenvironment through antibacterial, anti-inflammatory, and angiogenic activities, potentially shifting the surroundings from nonhealing to healing. The current review focuses on novel techniques, with a particular focus on recent revolutionary wound healing and infection control tactics based on nanomaterials, such as nanoparticles, nanocomposites, and scaffolds, which are discussed in depth. Furthermore, the effectiveness of nanoparticles as carriers for therapeutic compounds in wound-healing applications has been investigated which provide researchers an up-to-date sources on the use of nanomaterials and their creative ways that can improve wound-healing uses.

Keywords: gold nanoparticles (Au NPs), zinc oxide nanoparticles (ZnO NPs), wounds caring, sliver nanoparticle (Ag NPs)

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Received: 23 June 2023
Revised: 15 August 2023
Accepted: 13 September 2023
Published: 07 November 2023
Issue date: December 2023

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