Open Access
Issue
Published:
12 June 2023
Design, Synthesis, and Optimization of Silver Nanoparticles Using an Artocarpus heterophyllus Lam. Leaf Extract and Its Antibacterial Application
),
Download citation
1514
Views
305
Downloads
0
Crossref
N/A
WoS
0
Scopus
N/A
CSCD
In this study, the synthesis of nanoparticles and their biological evaluation were carried out. A green synthetic approach synthesized silver nanoparticles (AHAgNPs) using an Artocarpus heterophyllus leaf extract. Parameter optimization was performed using Design Expert Ver. 13. The effects of variables like the concentration on the response, particle size, and entrapment efficiency of synthesized AHAgNPs were monitored via analysis of variance. The optimized AgNPs were characterized using ultraviolet–visible spectroscopy and Fourier transform infrared spectroscopy. Scanning electron microscopy and transmission electron microscopy were used to determine the size and shape of nanoparticles. In vitro, antioxidant and antimicrobial potential were determined using standard protocols. The optimized nanoparticles were spherical, with an average 100–110 nm particle diameter. The synthesized nanoparticles showed effective antioxidant, antibacterial, and antifungal activity. In addition, AHAgNPs showed increased biological activities.
menu
Design, Synthesis, and Optimization of Silver Nanoparticles Using an Artocarpus heterophyllus Lam. Leaf Extract and Its Antibacterial Application
),
Abstract
In this study, the synthesis of nanoparticles and their biological evaluation were carried out. A green synthetic approach synthesized silver nanoparticles (AHAgNPs) using an Artocarpus heterophyllus leaf extract. Parameter optimization was performed using Design Expert Ver. 13. The effects of variables like the concentration on the response, particle size, and entrapment efficiency of synthesized AHAgNPs were monitored via analysis of variance. The optimized AgNPs were characterized using ultraviolet–visible spectroscopy and Fourier transform infrared spectroscopy. Scanning electron microscopy and transmission electron microscopy were used to determine the size and shape of nanoparticles. In vitro, antioxidant and antimicrobial potential were determined using standard protocols. The optimized nanoparticles were spherical, with an average 100–110 nm particle diameter. The synthesized nanoparticles showed effective antioxidant, antibacterial, and antifungal activity. In addition, AHAgNPs showed increased biological activities.
References(94)
D. Blondeau, L. Roy, S. Dumont, et al. Physicians' and pharmacists' attitudes toward the use of sedation at the end of life: Influence of prognosis and type of suffering. Journal of Palliative Care, 2005, 21(4): 238−245. https://doi.org/10.1177/082585970502100402
L. Zhang, F.X. Gu, J.M. Chan, et al. Nanoparticles in medicine: Therapeutic applications and developments. Clinical Pharmacology and Therapeutics, 2008, 83(5): 761−769. https://doi.org/10.1038/sj.clpt.6100400
S. Kundu, V. Maheshwari, S.J. Niu, et al. Polyelectrolyte mediated scalable synthesis of highly stable silver nanocubes in less than a minute using microwave irradiation. Nanotechnology, 2008, 19(6): 065604. https://doi.org/10.1088/0957-4484/19/6/065604
K. Okitsu, Y. Mizukoshi, T.A. Yamamoto, et al. Sonochemical synthesis of gold nanoparticles on chitosan. Materials Letters, 2007, 61(16): 3429−3431. https://doi.org/10.1016/j.matlet.2006.11.090
P.P. Gan, S.H. Ng, Y. Huang, et al. Green synthesis of gold nanoparticles using palm oil mill effluent (POME): A low-cost and eco-friendly viable approach. Bioresource Technology, 2012, 113: 132−135. https://doi.org/10.1016/j.biortech.2012.01.015
K.B. Narayanan, N. Sakthivel. Biological synthesis of metal nanoparticles by microbes. Advances in Colloid and Interface Science, 2010, 156(1–2): 1−13. https://doi.org/10.1016/j.cis.2010.02.001
S. Narayanan, B.N. Sathy, U. Mony, et al. Biocompatible magnetite/gold nanohybrid contrast agents via green chemistry for MRI and CT bioimaging. ACS Applied Materials &Interfaces, 2012, 4(1): 251−260. https://doi.org/10.1021/am201311c
Sharma, H. S., Ali, S. F., Hussain, S. M., Schlager, J. J., Sharma, A. Influence of engineered nanoparticles from metals on the blood-brain barrier permeability, cerebral blood flow, brain edema and neurotoxicity. An experimental study in the rat and mice using biochemical and morphological approaches. Journal of Nanoscience and Nanotechnology, 2009, 9(8): 5055−5072. https://doi.org/10.1166/jnn.2009.GR09
L. Castro, M.L. Blázquez, J.A. Muñoz, et al. Biological synthesis of metallic nanoparticles using algae. IET Nanobiotechnology, 2013, 7(3): 109−116. https://doi.org/10.1049/iet-nbt.2012.0041
S. Poulose, T. Panda, P.P. Nair, et al. Biosynthesis of silver nanoparticles. Journal of Nanoscience and Nanotechnology, 2014, 14(2): 2038−2049. https://doi.org/10.1166/jnn.2014.9019
K. Vithiya, S. Sen. Biosynthesis of nanoparticles. International Jornal of Pharmaceutical Science and Research, 2011, 2(11): 2781−2785.
S. Sunkar, C.V. Nachiyar. Biogenesis of antibacterial silver nanoparticles using the endophytic bacterium Bacillus cereus isolated from Garcinia xanthochymus. Asian Pacific Journal of Tropical Biomedicine, 2012, 2(12): 953−959. https://doi.org/10.1016/S2221-1691(13)60006-4
N. Madubuonu, S.O. Aisida, I. Ahmad, et al. Bio-inspired iron oxide nanoparticles using Psidium guajava aqueous extract for antibacterial activity. Applied Physics A:Materials Science and Processing, 2020, 126(1): 1−8. https://doi.org/10.1007/s00339-019-3249-6
S. Das, A. Das, A. Maji, et al. A compact study on impact of multiplicative Streblus asper inspired biogenic silver nanoparticles as effective photocatalyst, good antibacterial agent and interplay upon interaction with human serum albumin. Journal of Molecular Liquids, 2018, 259: 18−29. https://doi.org/10.1016/j.molliq.2018.02.111
E.C. Njagi, H. Huang, L. Stafford, et al. Biosynthesis of iron and silver nanoparticles at room temperature using aqueous sorghum bran extracts. Langmuir:the ACS Journal of Surfaces and Colloids, 2011, 27(1): 264−271. https://doi.org/10.1021/la103190n
R. Joseph, A. Naugolny, M. Feldman, et al. Cationic pillararenes potently inhibit biofilm formation without affecting bacterial growth and viability. Journal of the American Chemical Society, 2016, 138(3): 754−757. https://doi.org/10.1021/jacs.5b11834
H. C. Flemming, J. Wingender, U. Szewzyk, et al. Biofilms: An emergent form of bacterial life. Nature Reviews Microbiology, 2016, 14(9): 563−575. https://doi.org/10.1038/nrmicro.2016.94
J.H. Wu, F.Y. Li, X. Hu, et al. Responsive assembly of silver nanoclusters with a biofilm locally amplified bactericidal effect to enhance treatments against multi-drug-resistant bacterial infections. ACS Central Science, 2019, 5(8): 1366−1376. https://doi.org/10.1021/acscentsci.9b00359
A.K. Gupta, M.A. Rather, A. Kumar Jha, et al. Artocarpus lakoocha roxb. and artocarpus heterophyllus lam. flowers: New sources of bioactive compounds. Plants, 2020, 9(10): 1329. https://doi.org/10.3390/plants9101329
K.E. Jones, N.G. Patel, M.A. Levy, et al. Global trends in emerging infectious diseases. Nature, 2008, 451(7181): 990−993. https://doi.org/10.1038/nature06536
S.L. Jagadeesh, B.S. Reddy, G.S.K. Swamy, et al. Chemical composition of jackfruit (Artocarpus heterophyllus Lam.) selections of Western Ghats of India. Food Chemistry, 2007, 102(1): 361−365. https://doi.org/10.1016/j.foodchem.2006.05.027
R.A.S.N. Ranasinghe, S.D.T. Maduwanthi, R.A.U.J. Marapana. Nutritional and health benefits of jackfruit (Artocarpus heterophyllus Lam.): A review. International Journal of Food Science, 2019, 2019: 4327183. https://doi.org/10.1155/2019/4327183
R. Srivastava, A. Singh. Jackfruit (Artocarpus heterophyllus Lam) Biggest Fruit with High Nutritional and Pharmacological Values: A Review. International Journal of Current Microbiology and Applied Sciences, 2020, 9(8): 764−774. https://doi.org/10.20546/ijcmas.2020.908.082
F. Chahud, L.N.Z. Ramalho, F.S. Ramalho, et al. The lectin KM+ induces corneal epithelial wound healing in rabbits. International Journal of Experimental Pathology, 2009, 90(2): 166−173. https://doi.org/10.1111/j.1365-2613.2008.00626.x
S.C. Fang, C.L. Hsu, G.C. Yen. Anti-inflammatory effects of phenolic compounds isolated from the fruits of Artocarpus heterophyllus. Journal of Agricultural and Food Chemistry, 2008, 56(12): 4463−4468. https://doi.org/10.1021/jf800444g
M.B. Trindade, J.L.S. Lopes, A. Soares-Costa, et al. Structural characterization of novel chitin-binding lectins from the genus Artocarpus and their antifungal activity. Biochimica et Biophysica Acta - Proteins and Proteomics, 2006, 1764(1): 146−152. https://doi.org/10.1016/j.bbapap.2005.09.011
M.R. Fernando, N. Wickramasinghe, M.I. Thabrew, et al. Effect of Artocarpus heterophyllus and Asteracanthus longifolia on glucose tolerance in normal human subjects and in maturity-onset diabetic patients. Journal of Ethnopharmacology, 1991, 31(3): 277−282. https://doi.org/10.1016/0378-8741(91)90012-3
A. Eve, A.A. Aliero, D. Nalubiri, et al. In vitro antibacterial activity of crude extracts of artocarpus heterophyllus seeds against selected diarrhoea-causing superbug bacteria. The Scientific World Journal, 2020, 2020: 9813970. https://doi.org/10.1155/2020/9813970
A. Agarwal, A. Kumar, B.K. Singh, et al. A review on extraction and phytochemical screening methods. Research in Pharmacy and Health Sciences, 2016, 2(2): 130−137. https://doi.org/10.32463/rphs.2016.v02i02.25
F.N. Ko, Z.J. Cheng, C.N. Lin, et al. Scavenger and antioxidant properties of prenylflavones isolated from Artocarpus heterophyllus. Free Radical Biology &Medicine, 1998, 25(2): 160−168. https://doi.org/10.1016/S0891-5849(98)00031-8
P.S. Sreeja Devi, N.S. Kumar, K.K. Sabu. Phytochemical profiling and antioxidant activities of different parts of Artocarpus heterophyllus Lam. (Moraceae): A review on current status of knowledge. Future Journal of Pharmaceutical Sciences, 2021, 7: 30. https://doi.org/10.1186/s43094-021-00178-7
A.K. Nayak, M.S. Hasnain, J. Malakar. Development and optimization of hydroxyapatite-ofloxacin implants for possible bone delivery in osteomyelitis treatment. Current Drug Delivery, 2013, 10(2): 241−250. https://doi.org/10.2174/1567201811310020008
M.S. Alam, A. Garg, F.H. Pottoo, et al. Gum ghatti mediated, one pot green synthesis of optimized gold nanoparticles: Investigation of process-variables impact using Box-Behnken based statistical design. International Journal of Biological Macromolecules, 2017, 104(Pt A): 758−767. https://doi.org/10.1016/j.ijbiomac.2017.05.129
Z.Z. Ge, M.Y. Yang, Y.L. Wang, et al. Preparation and evaluation of orally disintegrating tablets of taste masked phencynonate HCl using ion-exchange resin. Drug Development and Industrial Pharmacy, 2015, 41(6): 934−941. https://doi.org/10.3109/03639045.2014.914529
M.S. Hasnain, S.A. Ansari, S. Rao, et al. QbD-Driven Development and Validation of Liquid Chromatography Tandem Mass Spectrometric Method for the Quantitation of Sildenafil in Human Plasma. Journal of Chromatographic Science, 2017, 55(6): 587−594. https://doi.org/10.1093/chromsci/bmx010
M.S. Hasnain, S. Rao, M.K. Singh, et al. Development and validation of LC-MS/MS method for the quantitation of lenalidomide in human plasma using Box-Behnken experimental design. The Analyst, 2013, 138(5): 1581−1588. https://doi.org/10.1039/c2an36701g
M.S. Hasnain, S. Rao, M.K. Singh, et al. Development and validation of an improved LC-MS/MS method for the quantification of desloratadine and its metabolite in human plasma using deutrated desloratadine as internal standard. Journal of Pharmacy and Bioallied Sciences, 2013, 5(1): 74−79. https://doi.org/10.4103/0975-7406.106571
A.K. Nayak, S. Kalia, M.S. Hasnain. Optimization of aceclofenac-loaded pectinate-poly(vinyl pyrrolidone) beads by response surface methodology. International Journal of Biological Macromolecules, 2013, 62: 194−202. https://doi.org/10.1016/j.ijbiomac.2013.08.043
A.K Nayak, D. Pal, J. Pradhan, et al. Fenugreek seed mucilage-alginate mucoadhesive beads of metformin HCl: Design, optimization and evaluation. International Journal of Biological Macromolecules, 2013, 54: 144−154. https://doi.org/10.1016/j.ijbiomac.2012.12.008
A.K. Nayak, D. Pal, M.S. Hasnain. Development, optimization and in vitro-in vivo evaluation of pioglitazone-loaded jackfruit seed starch-alginate beads. Current Drug Delivery, 2013, 10: 608−619. https://doi.org/10.2174/1567201811310050012
J. Malakar, K. Das, A.K. Nayak. Statistical optimization in formulation development of in situ cross-linked matrix tablets for sustained salbutamol sulfate release. Polymer Medicine, 2014, 44: 221−230.
N. Prabhu, D.T. Raj, K. Yamuna Gowri, et al. Synthesis of silver phyto nanoparticles and their antibacterial efficacy. Digest Journal of Nanomaterials and Biostructures, 2010, 5(1): 185−189.
R.R. Chavan, S.D. Bhinge, M.A. Bhutkar, et al. Characterization, antioxidant, antimicrobial and cytotoxic activities of green synthesized silver and iron nanoparticles using alcoholic Blumea eriantha DC plant extract. Materials Today Communications, 2020, 24: 101320. https://doi.org/10.1016/j.mtcomm.2020.101320
Y. Mi, J. Zhang, L. Zhang, et al. Synthesis, characterization, and evaluation of nanoparticles loading adriamycin based on 2-hydroxypropyltrimethyl ammonium chloride chitosan grafting folic acid. Polymers, 2021, 13(14): 2229. https://doi.org/10.3390/polym13142229
M.A. Hossain, K.A. AL-Raqmi, Z.H. AL-Mijizy, et al. Study of total phenol, flavonoids contents and phytochemical screening of various leaves crude extracts of locally grown Thymus vulgaris. Asian Pacific Journal of Tropical Biomedicine, 2013, 3(9): 705−710. https://doi.org/10.1016/S2221-1691(13)60142-2
L.L. Mensor, F.S. Menezes, G.G. Leitão, et al. Screening of Brazilian plant extracts for antioxidant activity by the use of DPPH free radical method. Phytotherapy Research, 2001, 15(2): 127−130. https://doi.org/10.1002/ptr.687
R. Mathur, R. Vijayvergia. Determination of Total Flavonoid and Phenol Content in Mimusops Elengi Linn. International Journal of Pharmaceutical Sciences and Research, 2017, 8(12): 5282−5285. https://doi.org/10.13040/IJPSR.0975-8232.8(12).5282-85
M. Irshad. Antioxidant and antimicrobial activities of essential oil of Skimmea laureola growing wild in the State of Jammu and Kashmir. Journal of Medicinal Plants Research, 2012, 6(9): 1680−1684. https://doi.org/10.5897/jmpr11.1470
S.D. Bhinge, M.A. Bhutkar, D.S. Randive, et al. Formulation development and evaluation of antimicrobial polyherbal gel. Annales Pharmaceutiques Francaises, 2017, 75(5): 349−358. https://doi.org/10.1016/j.pharma.2017.04.006
S.S. Shankar, A. Rai, A. Ahmad, et al. Rapid synthesis of Au, Ag, and bimetallic Au core-Ag shell nanoparticles using Neem (Azadirachta indica) leaf broth. Journal of Colloid and Interface Science, 2004, 275(2): 496−502. https://doi.org/10.1016/j.jcis.2004.03.003
A.D. Dwivedi, K. Gopal. Biosynthesis of silver and gold nanoparticles using Chenopodium album leaf extract. Colloids and Surfaces A:Physicochemical and Engineering Aspects, 2010, 369(1–3): 27−33. https://doi.org/10.1016/j.colsurfa.2010.07.020
J. Hussein, M.E. El-Naggar, M.M.G. Fouda, et al. The efficiency of blackberry loaded AgNPs, AuNPs and Ag@AuNPs mediated pectin in the treatment of cisplatin-induced cardiotoxicity in experimental rats. International Journal of Biological Macromolecules, 2020, 159: 1084−1093. https://doi.org/10.1016/j.ijbiomac.2020.05.115
A.K. Jha, K. Prasad. Green synthesis of silver nanoparticles using cycas leaf. International Journal of Green Nanotechnology:Physics and Chemistry, 2010, 1(2): P110−P117. https://doi.org/10.1080/19430871003684572
M. Mourabet, A. El Rhilassi, H. El Boujaady, et al. Use of response surface methodology for optimization of fluoride adsorption in an aqueous solution by Brushite. Arabian Journal of Chemistry, 2017, 10: S3292−S3302. https://doi.org/10.1016/j.arabjc.2013.12.028
A.-R. Phull, Q. Abbas, A. Ali, et al. Antioxidant, cytotoxic and antimicrobial activities of green synthesized silver nanoparticles from crude extract of Bergenia ciliata. Future Journal of Pharmaceutical Sciences, 2016, 2(1): 31−36. https://doi.org/10.1016/j.fjps.2016.03.001
R.W. Rajesh, L.R. Jaya, K.S. Niranjan, et al. Phytosynthesis of silver nanoparticle using Gliricidia sepium (Jacq.). Current Nanoscience, 2009, 5(1): 117−122. https://doi.org/10.2174/157341309787314674
S.M. Roopan, Rohit, G. Madhumitha, et al. Low-cost and eco-friendly phyto-synthesis of silver nanoparticles using Cocos nucifera coir extract and its larvicidal activity. Industrial Crops and Products, 2013, 43(1): 631−635. https://doi.org/10.1016/j.indcrop.2012.08.013
K.P. Shejawal, D.S. Randive, S.D. Bhinge, et al. Green synthesis of silver and iron nanoparticles of isolated proanthocyanidin: its characterization, antioxidant, antimicrobial, and cytotoxic activities against COLO320DM and HT29. Journal of Genetic Engineering and Biotechnology, 2020, 18: 43. https://doi.org/10.1186/s43141-020-00058-2
Z.K. Taha, S.N. Hawar, G.M. Sulaiman. Extracellular biosynthesis of silver nanoparticles from Penicillium italicum and its antioxidant, antimicrobial and cytotoxicity activities. Biotechnology Letters, 2019, 41(8–9): 899−914. https://doi.org/10.1007/s10529-019-02699-x
R. Veerasamy, T.Z. Xin, S. Gunasagaran, et al. Biosynthesis of silver nanoparticles using mangosteen leaf extract and evaluation of their antimicrobial activities. Journal of Saudi Chemical Society, 2011, 15(2): 113−120. https://doi.org/10.1016/j.jscs.2010.06.004
Y. Yamamoto, S. Tamura, T. Kumon, et al. A case of mucocele of the appendix; diffusion weighted MRI appearance. Japanese Journal of Clinical Radiology, 2007, 52(10): 1265−1269.
A.K. Jha, K. Prasad, K. Prasad, et al. Plant system: Nature’s nanofactory. Colloids and Surfaces B,Biointerfaces, 2009, 73(2): 219−223. https://doi.org/10.1016/j.colsurfb.2009.05.018
S.P. Dubey, M. Lahtinen, M. Sillanpää. Green synthesis and characterizations of silver and gold nanoparticles using leaf extract of Rosa rugosa. Colloids and Surfaces A:Physicochemical and Engineering Aspects, 2010, 364: 34−41. https://doi.org/10.1016/j.colsurfa.2010.04.023
G. Arya, R.M. Kumari, N. Gupta, et al. Green synthesis of silver nanoparticles using Prosopis juliflora bark extract: Reaction optimization, antimicrobial and catalytic activities. Artificial Cells,Nanomedicine,and Biotechnology, 2018, 46(5): 985−993. https://doi.org/10.1080/21691401.2017.1354302
J. Das, P. Velusamy. Biogenic synthesis of antifungal silver nanoparticles using aqueous stem extract of banana. Nano Biomedicine and Engineering, 2013, 5(1): 34−38. https://doi.org/10.5101/nbe.v5i1
M.S. Hasnain, M.N. Javed, M.S. Alam, et al. Purple heart plant leaves extract-mediated silver nanoparticle synthesis: Optimization by Box-Behnken design. Materials Science &Engineering C,Materials for Biological Applications, 2019, 99: 1105−1114. https://doi.org/10.1016/j.msec.2019.02.061
M.J. Kim, J.N. Hyun, J.A. Kim, et al. Relationship between phenolic compounds, anthocyanins content and antioxidant activity in colored barley germplasm. Journal of Agricultural and Food Chemistry, 2007, 55(12): 4802−4809. https://doi.org/10.1021/jf0701943
G. Nikaeen, S. Yousefinejad, S. Rahmdel, et al. Central composite design for optimizing the biosynthesis of silver nanoparticles using plantago major extract and investigating antibacterial, antifungal and antioxidant activity. Scientific Reports, 2020, 10(1): 9642. https://doi.org/10.1038/s41598-020-66357-3
A.M. Othman, M.A. Elsayed, A.M. Elshafei, et al. Application of response surface methodology to optimize the extracellular fungal mediated nanosilver green synthesis. Journal of Genetic Engineering and Biotechnology, 2017, 15(2): 497−504. https://doi.org/10.1016/j.jgeb.2017.08.003
N. Rahman, P. Varshney. Assessment of ampicillin removal efficiency from aqueous solution by polydopamine/zirconium(iv) iodate: Optimization by response surface methodology. RSC Advances, 2020, 10(34): 20322−20337. https://doi.org/10.1039/d0ra02061c
C. Chen, S. Mu. The electrochemical preparation of polyphenol with conductibility. Chinese Journal of Polymer Science, 2002, 20: 309−316.
N.J. Reddy, D. Nagoor Vali, M. Rani, et al. Evaluation of antioxidant, antibacterial and cytotoxic effects of green synthesized silver nanoparticles by Piper longum fruit. Materials Science &Engineering C,Materials for Biological Applications, 2014, 34: 115−122. https://doi.org/10.1016/j.msec.2013.08.039
S.V. Kumar, S.P. Kumar, D. Rupesh, et al. Journal of Chemical and Pharmaceutical Research preparations. Journal of Chemical and Pharmaceutical Research, 2011, 3(1): 675−684.
D.M. Kasote, S.S. Katyare, M.V. Hegde, et al. Significance of antioxidant potential of plants and its relevance to therapeutic applications. International Journal of Biological Sciences, 2015, 11(8): 982−991. https://doi.org/10.7150/ijbs.12096
Munteanu, I.G., Apetrei, C. Analytical methods used in determining antioxidant activity: A review. International Journal of Molecular Sciences, 2021, 22(7): 3380. https://doi.org/10.3390/ijms22073380
H.S. Omar, H.A. El-Beshbishy, Z. Moussa, et al. Antioxidant activity of Artocarpus heterophyllus Lam. (Jack Fruit) leaf extracts: Remarkable attenuations of hyperglycemia and hyperlipidemia in streptozotocin-diabetic rats. The Scientific World Journal, 2011, 11: 788−800. https://doi.org/10.1100/tsw.2011.71
N. Thapa, P. Thapa, J. Bhandari, et al. Study of Phytochemical, Antioxidant and Antimicrobial Activity of Artocarpus heterophyllus. Nepal Journal of Biotechnology, 2016, 4(1): 47−53. https://doi.org/10.3126/njb.v4i1.16347
K. Ajisaka, Y. Oyanagi, T. Miyazaki, et al. Effect of the chelation of metal cation on the antioxidant activity of chondroitin sulfates. Bioscience,Biotechnology,and Biochemistry, 2016, 80(6): 1179−1185. https://doi.org/10.1080/09168451.2016.1141036
A. Saxena, R.M. Tripathi, F. Zafar, et al. Green synthesis of silver nanoparticles using aqueous solution of Ficus benghalensis leaf extract and characterization of their antibacterial activity. Materials Letters, 2012, 67: 91−94. https://doi.org/10.1016/j.matlet.2011.09.038
W. Gao, Y. Chen, Y. Zhang, et al. Nanoparticle-based local antimicrobial drug delivery. Advanced Drug Delivery Reviews, 2018, 127: 46−57. https://doi.org/10.1016/j.addr.2017.09.015
N.Y. Lee, W. C. Ko, P.R. Hsueh. Nanoparticles in the treatment of infections caused by multidrug-resistant organisms. Frontiers in Pharmacology, 2019, 10: 1153. https://doi.org/10.3389/fphar.2019.01153
G.R. Rudramurthy, M.K. Swamy, U.R. Sinniah, et al. Nanoparticles: Alternatives against drug-resistant pathogenic microbes. Molecules, 2016, 21(7): 836. https://doi.org/10.3390/molecules21070836
L.L. Wang, C. Hu, L.Q. Shao. The antimicrobial activity of nanoparticles: Present situation and prospects for the future. International Journal of Nanomedicine, 2017, 12: 1227−1249. https://doi.org/10.2147/IJN.S121956
B. Khameneh, R. Diab, K. Ghazvini, et al. Breakthroughs in bacterial resistance mechanisms and the potential ways to combat them. Microbial Pathogenesis, 2016, 95: 32−42. https://doi.org/10.1016/j.micpath.2016.02.009
N. Beyth, Y. Houri-Haddad, A. Domb, et al. Alternative antimicrobial approach: Nano-antimicrobial materials. Evidence-Based Complementary and Alternative Medicine:ECAM, 2015, 2015: 246012. https://doi.org/10.1155/2015/246012
M. Mühling, A. Bradford, J.W. Readman, et al. An investigation into the effects of silver nanoparticles on antibiotic resistance of naturally occurring bacteria in an estuarine sediment. Marine Environmental Research, 2009, 68(5): 278−283. https://doi.org/10.1016/j.marenvres.2009.07.001
R.Y. Pelgrift, A.J. Friedman. Nanotechnology as a therapeutic tool to combat microbial resistance. Advanced Drug Delivery Reviews, 2013, 65(13–14): 1803−1815. https://doi.org/10.1016/j.addr.2013.07.011
M.A. Bhutkar, D.S. Randive, S.D. Bhinge, et al. Development of gold, silver and iron nanoparticles of isolated berberine: Its characterization, antimicrobial, and cytotoxic activities against COLO320DM and Hela cells. Gold Bulletin, 2022, 55(1): 93−103. https://doi.org/10.1007/s13404-022-00309-9
R.R. Chavan, S.D. Bhinge, M.A. Bhutkar, et al. In vivo and in vitro hair growth-promoting effect of silver and iron nanoparticles synthesized via Blumea eriantha DC plant extract. Journal of Cosmetic Dermatology, 2021, 20(4): 1283−1297. https://doi.org/10.1111/jocd.13713
K.P. Shejawal, D.S. Randive, S.D. Bhinge, et al. Green synthesis of silver, iron and gold nanoparticles of lycopene extracted from tomato: Their characterization and cytotoxicity against COLO320DM, HT29 and Hella cell. Journal of Materials Science Materials in Medicine, 2021, 32(2): 19. https://doi.org/10.1007/s10856-021-06489-8
S. Maiti, D. Krishnan, G. Barman, et al. Antimicrobial activities of silver nanoparticles synthesized from Lycopersicon esculentum extract. Journal of Analytical Science and Technology, 2014, 5(1): 1−7. https://doi.org/10.1186/s40543-014-0040-3
Publication history
Copyright
Acknowledgements
The authors are thankful to Dr. S. A. Mohite, Principal, Rajarambapu College of Pharmacy, Kasegaon (Maharashtra) for providing the necessary facilities to carry out the research work.
Rights and permissions
This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (CC BY) (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
FEEDBACK 
TOP