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Journal of Neurorestoratology 2021, 9(3): 196-207 https://doi.org/10.26599/JNR.2021.9040022
Research Article | Open Access | Issue | Published: 22 December 2021

A novel intelligent microcatheter-shaping method for embolization of intracranial aneurysm

Show Author's Information Ling Song1,  Wei Ni2,  Wenzhi Wang1,  Guangming Yang1,  Jianjun Li1,  Xue Feng1,  Lan Qin1,  Wangsheng Lu1( ),  Yuxiang Gu2,  Yin Yin1( )
Union Strong (Beijing) Technology Co. Ltd., Beijing 100176, China
Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai 200040, China
Keywords:
model experiment, intracranial aneurysms, microcatheter shaping
Cite this article:
Song L, Ni W, Wang W, et al. A novel intelligent microcatheter-shaping method for embolization of intracranial aneurysm. Journal of Neurorestoratology, 2021, 9(3): 196-207. https://doi.org/10.26599/JNR.2021.9040022
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Abstract Full text About this article
Objective:

This study proposed and validated an intelligent microcatheter-shaping algorithm for interventional embolization of intracranial aneurysms.

Methods:

A stepwise microcatheter simulation algorithm constrained by a vessel center line was developed based on the geometry of aneurysms and parent arteries, and a collision correction factor of vessel walls was introduced to automatically calculate the optimal microcatheter path and tip shape. The efficacy of this intelligent shaping method was verified in an in vitro aneurysm model experiment.

Results:

The microcatheter path can be automatically generated using the intelligent microcatheter-shaping algorithm. Furthermore, the experiment verified that the delivery performance of an intelligently shaped microcatheter was excellent with 100% placement accuracy, superior to that of three pre-shaped microcatheters: straight (0°), 45°, and 90°. In three typical cases, the microcatheter could not be placed in the aneurysms successfully within 5 min with the aid of a microwire using a manual shaping scheme; however, it can be placed in the aneurysms successfully within 5 min using an intelligent microcatheter- shaping scheme, and the time of microcatheter placement in aneurysms was short.

Conclusion:

This intelligent microcatheter-shaping algorithm based on three-dimensional image data is effective and reasonable. This approach has advantages over standard pre-shaped microcatheters, with a potential clinical application value.


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Abstract
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About this article

A novel intelligent microcatheter-shaping method for embolization of intracranial aneurysm

Show Author's information Ling Song1, Wei Ni2, Wenzhi Wang1, Guangming Yang1, Jianjun Li1, Xue Feng1, Lan Qin1, Wangsheng Lu1( ), Yuxiang Gu2, Yin Yin1( )
Union Strong (Beijing) Technology Co. Ltd., Beijing 100176, China
Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai 200040, China

Abstract

Objective:

This study proposed and validated an intelligent microcatheter-shaping algorithm for interventional embolization of intracranial aneurysms.

Methods:

A stepwise microcatheter simulation algorithm constrained by a vessel center line was developed based on the geometry of aneurysms and parent arteries, and a collision correction factor of vessel walls was introduced to automatically calculate the optimal microcatheter path and tip shape. The efficacy of this intelligent shaping method was verified in an in vitro aneurysm model experiment.

Results:

The microcatheter path can be automatically generated using the intelligent microcatheter-shaping algorithm. Furthermore, the experiment verified that the delivery performance of an intelligently shaped microcatheter was excellent with 100% placement accuracy, superior to that of three pre-shaped microcatheters: straight (0°), 45°, and 90°. In three typical cases, the microcatheter could not be placed in the aneurysms successfully within 5 min with the aid of a microwire using a manual shaping scheme; however, it can be placed in the aneurysms successfully within 5 min using an intelligent microcatheter- shaping scheme, and the time of microcatheter placement in aneurysms was short.

Conclusion:

This intelligent microcatheter-shaping algorithm based on three-dimensional image data is effective and reasonable. This approach has advantages over standard pre-shaped microcatheters, with a potential clinical application value.

Keywords: model experiment, intracranial aneurysms, microcatheter shaping

References(22)

[1]
Ujiie H, Sato K, Onda H, et al. Clinical analysis of incidentally discovered unruptured aneurysms. Stroke 1993, 24(12): 1850-1856.
DOI Google Scholar
[2]
Li MH, Chen SW, Li YD, et al. Prevalence of unruptured cerebral aneurysms in Chinese adults aged 35 to 75 years: a cross-sectional study. Ann Intern Med 2013, 159(8): 514-521.
DOI Google Scholar
[3]
Brisman JL, Song JK, Newell DW. Cerebral aneurysms. N Engl J Med 2006, 355(9): 928-939.
DOI Google Scholar
[4]
Vlak MH, Algra A, Brandenburg R, et al. Prevalence of unruptured intracranial aneurysms, with emphasis on sex, age, comorbidity, country, and time period: a systematic review and meta-analysis. Lancet Neurol 2011, 10(7): 626-636.
DOI Google Scholar
[5]
van Gijn J, Kerr RS, Rinkel GJ. Subarachnoid haemorrhage. Lancet 2007, 369(9558): 306-318.
DOI Google Scholar
[6]
Molyneux AJ, Kerr RSC, Yu L-M, et al. International subarachnoid aneurysm trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomised comparison of effects on survival, dependency, seizures, rebleeding, subgroups, and aneurysm occlusion. Lancet 2005, 366(9488): 809-817.
DOI Google Scholar
[7]
Golnari P, Nazari P, Garcia RM, et al. Volumes, outcomes, and complications after surgical versus endovascular treatment of aneurysms in the United States (1993-2015): continued evolution versus steady-state after more than 2 decades of practice. J Neurosurg 2020, 134(3): 848-861.
DOI Google Scholar
[8]
Guo XL, Xue Q, Zhao JH, et al. Clinical diagnostic and therapeutic guidelines of stroke neurorestoration (2020 China version). J Neurorestoratol 2020, 8(4): 241-251.
DOI Google Scholar
[9]
Kwon BJ, Im S-H, Park JC, et al. Shaping and navigating methods of microcatheters for endovascular treatment of paraclinoid aneurysms. Neurosurgery 2010, 67(1): 34-40.
DOI Google Scholar
[10]
Ishibashi T, Takao H, Suzuki T, et al. Tailor-made shaping of microcatheters using three-dimensional printed vessel models for endovascular coil embolization. Comput Biol Med 2016, 77: 59-63.
DOI Google Scholar
[11]
Kim TG. Optimal microcatheter shaping method customized for a patient-specific vessel using a three- dimensional printer. J Cerebrovasc Endovasc Neurosurg 2021, 23(1): 16-22.
DOI Google Scholar
[12]
Lv XL, Jiang CH, Liang SK. Small ruptured and unruptured complex cerebral aneurysms: Single center experience of low-profile visualized intraluminal support stent. J Neurorestoratol 2019, 7(4): 235-241.
DOI Google Scholar
[13]
Lee HY, Ahn JS, Suh DC, et al. Z-shaped microcatheter tip shaping for embolization of aneurysms at the proximal A1 segment of the anterior cerebral artery: a technical note. Neurointervention 2011, 6(2): 95-99.
DOI Google Scholar
[14]
Ohshima T, Miyachi S, Matsuo N, et al. A novel approach involving a microcatheter tip during aneurysmal coil embolization: The Γ (gamma) tip method. Interv Neuroradiol 2019, 25(6): 681-684.
DOI Google Scholar
[15]
Xu Y, Tian W, Wei Z, et al. Microcatheter shaping using three-dimensional printed models for intracranial aneurysm coiling. J NeuroInterv Surg 2020. 12(3): 308-310.
DOI Google Scholar
[16]
Yamaguchi S, Ito O, Koyanagi Y, et al. Microcatheter shaping using intravascular placement during intracranial aneurysm coiling. Interv Neuroradiol 2017, 23(3): 249-254.
DOI Google Scholar
[17]
Nawka MT, Buhk J-H, Gellissen S, et al. A new method to statistically describe microcatheter tip position in patient-specific aneurysm models. J Neurointerv Surg 2019, 11(4): 425-430.
DOI Google Scholar
[18]
Lin CQ, Chen LK. Effect of hemorrhagic cerebrospinal fluid drainage on cognitive function after intracranial aneurysm clipping. Brain Sci Adv 2019, 5(1): 65-72.
DOI Google Scholar
[19]
Tack P, Victor J, Gemmel P, et al. 3D-printing techniques in a medical setting: a systematic literature review. Biomed Eng Online 2016, 15(1): 115-117.10.1186/s12938-016-0236-4
DOI Google Scholar
[20]
Namba K, Higaki A, Kaneko N, et al. Microcatheter shaping for intracranial aneurysm coiling using the 3-dimensional printing rapid prototyping technology: Preliminary result in the first 10 consecutive cases. World Neurosurg 2015, 84(1): 178-186.
DOI Google Scholar
[21]
Pakeliani D, Bleuler A, Chaykovska L, et al. Patient- specific rehearsal feasibility before endovascular repair of ruptured abdominal aortic aneurysm. J Endovasc Ther 2019, 26(6): 871-878.
DOI Google Scholar
[22]
Bairamian D, Liu SN, Eftekhar B. Virtual reality angiogram vs 3-dimensional printed angiogram as an educational tool-A comparative study. Neurosurgery 2019, 85(2): E343-E349.
DOI Google Scholar
Publication history
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Publication history

Received: 01 June 2021
Revised: 02 August 2021
Accepted: 09 August 2021
Published: 22 December 2021
Issue date: September 2021

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© The authors 2021

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This article is published with open access at http://jnr.tsinghuajournals.com

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