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Brainstem hemorrhage (mainly pontine hemorrhage caused by hypertension) has the clinical characteristics of acute onset, rapid progress, high mortality, and high disability rate. Due to the complexity of the brainstem’s anatomical structure and functional importance, it is generally recognized that brainstem treatment is difficult and risky, so it has been regarded as a restricted area of surgery. However, in recent years, continuous progress is being made in many areas, including microsurgical technology, stereotactic technology, robot-assisted surgery, neuroendoscopy, and theoretical and clinical practice of neurorestoration, aiding in the understanding, diagnosis, and treatment of brainstem hemorrhage injuries. The Chinese Association of Neurorestoratology (CANR; Preparatory) and the China Committee of International Association of Neurorestoratology (IANR-China Committee) organized relevant experts to formulate this clinical guideline to diagnose and restore damaged nerves after brainstem hemorrhages, promote a standardized diagnosis, and to neurorestoratologically treat this disease.


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Clinical neurorestorative therapeutic guideline for brainstem hemorrhage (2020 China version)

Show Author's information Lin Chen1Tao Chen2Gengsheng Mao3( )Baodong Chen4Mingchang Li5Hongbo Zhang6Haitao Xi7Xiaochun She8Zhouping Tang9Ping Zhang9Zhiqiang Zhang10Li Cong10Yijun Bao11Xiaofeng Yang12Siyuan Zhao1Chao He13Liang Wen12Ping Zhang14Mengzhou Xue15
Department of Neurosurgery, Dongzhimen Hospital, University of Chinese Medicine, Beijing 100700, China
Beijing Huicheng Medical Research Institute, Beijing 100048, China
Institute of Neurorestoratology, Third Medical Center of General Hospital of PLA, Beijing 100039, China
Department of Neurosurgery, Peking University Shenzhen Hospital, Shenzhen 518035, China
Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, China
Department of Neurosurgery, Zhujiang Hospital of Southern Medical University, The National Key Clinical Specialty, The Engineering Technology Research Center of Education Ministry of China, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, Guangzhou 510282, Guangdong, China
Department of Neurology, Beijing Rehabilitation Hospital of Capital Medical University, Beijing 100144, China
Department of Neurosurgery, Rudong People's Hospital, Nantong 226400, Jiangsu, China
Department of Neurology, Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430030, Hubei, China
Department of Neurosurgery, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Province Hospital of Chinese Medical, Guangzhou 510120, Guangdong, China
Department of Neurosurgery, Fourth Hospital of China Medical University, Shenyang 110084, Liaoning, China
Department of Neurosurgery, The First Affiliated Hospital, Zhengjiang University School of Medicine, Hangzhou 310003, Zhejiang, China
Department of Neurosurgery, Zhuji Affiliated Hospital of Wenzhou Medical University, Zhuji 311800, Zhejiang, China
Department of Neurology, Shenzhen University General Hospital, Shenzhen 518055, China
The Department of Cerebrovascular Diseases, The Second Affiliated Hospital of Zhengzhou University, Henan Joint International Laboratory of Intracerebral Hemorrhagic Brain Injury, Zhengzhou 450001, Henan, China

Abstract

Brainstem hemorrhage (mainly pontine hemorrhage caused by hypertension) has the clinical characteristics of acute onset, rapid progress, high mortality, and high disability rate. Due to the complexity of the brainstem’s anatomical structure and functional importance, it is generally recognized that brainstem treatment is difficult and risky, so it has been regarded as a restricted area of surgery. However, in recent years, continuous progress is being made in many areas, including microsurgical technology, stereotactic technology, robot-assisted surgery, neuroendoscopy, and theoretical and clinical practice of neurorestoration, aiding in the understanding, diagnosis, and treatment of brainstem hemorrhage injuries. The Chinese Association of Neurorestoratology (CANR; Preparatory) and the China Committee of International Association of Neurorestoratology (IANR-China Committee) organized relevant experts to formulate this clinical guideline to diagnose and restore damaged nerves after brainstem hemorrhages, promote a standardized diagnosis, and to neurorestoratologically treat this disease.

Keywords: surgery, brainstem hemorrhage, neurorestoratological treatment, guideline

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Received: 19 October 2020
Revised: 20 December 2020
Accepted: 28 December 2020
Published: 07 February 2021
Issue date: December 2020

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© The authors 2020.

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