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Objectives:

Even though low-profile visualized intraluminal support (LVIS) device is used extensively currently and provide intraluminal support in complex cerebral aneurysm embolization, only few studies have reported its clinical results. This study presents the results of patients treated with LVIS.

Patients and methods:

Cerebral aneurysms with an undefined neck, fusiform shape, and blood blister-like aneurysms that were treated with LVIS between May 2017 and May 2019 were reviewed retrospectively.

Results:

Overall, 112 aneurysms in 104 patients were treated using LVIS, and 105 LVISs were placed. Of these, 101 aneurysms (90%) were small (< 10 mm) in size, 17 were fusiform aneurysms, and 3 were blood blister-like aneurysms. Overall, 39 patients suffered a subarachnoid hemorrhage and 65 had no bleeding history. 2 patients died of internal carotid artery (ICA) thrombosis, resulting in 1.9% mortality rate. Follow-up angiography was obtained in 68 patients (65%), and the complete obliteration rate was 98.5% in 6–12 months.

Conclusion:

The LVIS is a safe and effective treatment for small ruptured or unruptured complex intracranial aneurysms.


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Small ruptured and unruptured complex cerebral aneurysms: Single center experience of low-profile visualized intraluminal support stent

Show Author's information Xianli Lv( )Chuhan JiangShikai Liang
Department of Neurosurgery, School of Clinical Medicine, Beijing Tsinghua Changgung Hospital, Tsinghua University, Beijing 102218, China

Abstract

Objectives:

Even though low-profile visualized intraluminal support (LVIS) device is used extensively currently and provide intraluminal support in complex cerebral aneurysm embolization, only few studies have reported its clinical results. This study presents the results of patients treated with LVIS.

Patients and methods:

Cerebral aneurysms with an undefined neck, fusiform shape, and blood blister-like aneurysms that were treated with LVIS between May 2017 and May 2019 were reviewed retrospectively.

Results:

Overall, 112 aneurysms in 104 patients were treated using LVIS, and 105 LVISs were placed. Of these, 101 aneurysms (90%) were small (< 10 mm) in size, 17 were fusiform aneurysms, and 3 were blood blister-like aneurysms. Overall, 39 patients suffered a subarachnoid hemorrhage and 65 had no bleeding history. 2 patients died of internal carotid artery (ICA) thrombosis, resulting in 1.9% mortality rate. Follow-up angiography was obtained in 68 patients (65%), and the complete obliteration rate was 98.5% in 6–12 months.

Conclusion:

The LVIS is a safe and effective treatment for small ruptured or unruptured complex intracranial aneurysms.

Keywords: reconstruction, complex, cerebral aneurysms, low-profile visualized intraluminal support device, stent

References(23)

[1]
F Alghamdi, B Mine, R Morais, et al. Stent-assisted coiling of intracranial aneurysms located on small vessels: midterm results with the LVIS Junior stent in 40 patients with 43 aneurysms. Neuroradiology. 2016, 58(7): 665-671.
[2]
F Cagnazzo, M Cappucci, PH Lefevre, et al. Treatment of intracranial aneurysms with self-expandable braided stents: A systematic review and meta-analysis. AJNR Am J Neuroradiol. 2018, 39(11): 2064-2069.
[3]
YD Cho, CH Sohn, HS Kang, et al. Coil embolization of intracranial saccular aneurysms using the low-profile visualized intraluminal support (LVIS™) device. Neuroradiology. 2014, 56(7): 543-551.
[4]
X Feng, ZH Qian, P Liu, et al. Comparison of recanalization and in-stent stenosis between the low-profile visualized intraluminal support stent and enterprise stent-assisted coiling for 254 intracranial aneurysms. World Neurosurg. 2018, 109: e99-e104.
[5]
ZZ Feng, YB Fang, Y Xu, et al. The safety and efficacy of low profile visualized intraluminal support (LVIS) stents in assisting coil embolization of intracranial saccular aneurysms: a single center experience. J Neurointerv Surg. 2016, 8(11): 1192-1196.
[6]
D Fiorella, A Boulos, AS Turk, et al. The safety and effectiveness of the LVIS stent system for the treatment of wide-necked cerebral aneurysms: final results of the pivotal US LVIS trial. J Neurointerv Surg. 2019, 11(4): 357-361.
[7]
HJ Ge, X Lv, XJ Yang, et al. LVIS stent versus enterprise stent for the treatment of unruptured intracranial aneurysms. World Neurosurg. 2016, 91: 365-370.
[8]
BA Gross, WJ Ares, AF Ducruet, et al. A clinical comparison of Atlas and LVIS Jr stent-assisted aneurysm coiling. J Neurointerv Surg. 2019, 11(2): 171-174.
[9]
JA Grossberg, RA Hanel, G Dabus, et al. Treatment of wide-necked aneurysms with the low-profile visualized intraluminal support (LVIS jr) device: a multicenter experience. J Neurointerv Surg. 2017, 9(11): 1098-1102.
[10]
C Iosif, M Piotin, S Saleme, et al. Safety and effectiveness of the low profile visualized intraluminal support (LVIS and LVIS jr) devices in the endovascular treatment of intracranial aneurysms: results of the TRAIL multicenter observational study. J Neurointerv Surg. 2018, 10(7): 675-681.
[11]
M Martínez-Galdámez, K Orlov, K Kadziolka, et al. Safety and efficacy of intracranial aneurysm embolization using the "combined remodeling technique" : low-profile stents delivered through double lumen balloons: a multicenter experience. Neuroradiology. 2019, in press, .
[12]
M Negrotto, R Crosa, W Casagrande. Assisted coiling using LEO baby or LVIS jr stents: report of six cases. Interv Neuroradiol. 2015, 21(5): 566-574.
[13]
SY Park, JS Oh, HJ Oh, et al. Safety and efficacy of low-profile, self-expandable stents for treatment of intracranial aneurysms: initial and midterm results - A systematic review and meta-analysis. Interv Neurol. 2017, 6(3/4): 170-182.
[14]
W Poncyljusz, P Biliński, K Safranow, et al. The LVIS/LVIS Jr. stents in the treatment of wide- neck intracranial aneurysms: multicentre registry. J Neurointerv Surg. 2015, 7(7): 524-529.
[15]
CC Wang, YN Wu, ZZ Feng, et al. Preliminary experience with the use of low profile visualized intraluminal support device in basilar artery for aneurysm treatment. J Neurointerv Surg. 2019, 11(4): 405-410.
[16]
CC Wang, YB Fang, P Zhang, et al. Reconstructive endovascular treatment of vertebral artery dissecting aneurysms with the low-profile visualized intraluminal support (LVIS) device. PLoS One. 2017, 12(6): e0180079.
[17]
J Wang, J Vargas, A Spiotta, et al. Stent-assisted coiling of cerebral aneurysms: a single-center clinical and angiographic analysis. J Neurointerv Surg. 2018, 10(7): 687-692.
[18]
P Wu, PE Ocak, DH Wang, et al. Endovascular treatment of ruptured tiny intracranial aneurysms with low-profile visualized intraluminal support device. J Stroke Cerebrovasc Dis. 2019, 28(2): 330-337.
[19]
ZY Yan, K Zheng, Y Xiong, et al. Intracranial complex ruptured aneurysms coiled with overlapping low-profile visualized intraluminal support stents: another available option for complex ruptured intracranial aneurysms. World Neurosurg. 2019, 125: e22-e28.
[20]
DH Yoo, YD Cho, J Moon, et al. Long-term outcomes of Low-profile Visualized Intraluminal Support device usage in stent-assisted coiling of intracranial aneurysm. J Clin Neurosci. 2018, 50: 287-291.
[21]
XG Zhang, JJ Zhong, H Gao, et al. Endovascular treatment of intracranial aneurysms with the LVIS device: a systematic review. J Neurointerv Surg. 2017, 9(6): 553-557.
[22]
DY Zhu, YB Fang, PF Yang, et al. Overlapped stenting combined with coiling for blood blister-Like aneurysms: comparison of low-profile visualized intraluminal support (LVIS) stent and non-LVIS stent. World Neurosurg. 2017, 104: 729-735.
[23]
X Lv, CH Jiang, ZX Wu, et al. Complex cerebral aneurysms: intra-luminal reconstruction using Pipeline flow-diverting stent and the obliteration mechanism. Neuroradiol J. 2019, in press, .
Publication history
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Publication history

Received: 06 September 2019
Revised: 29 November 2019
Accepted: 24 December 2019
Published: 17 January 2020
Issue date: December 2019

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© The authors 2019

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This article is published with open access at http://jnr.tsinghuajournals.com

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