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Dural defects are a common problem in clinical practice, and various types of dural substitutes have been used to deal with dural defects. These play an important role in dural repair. Dural substitutes have gradually reached researchers, neurosurgeons, and patients for approval. This article summarizes the structural characteristics of the dura mater and its regeneration after injury, and reviews the state of progress in research and application. It will provide a reference for the development and application of dural substitutes.


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Research and application progress on dural substitutes

Show Author's information Weizuo WangQiang Ao( )
Department of Tissue Engineering, China Medical University, Shenyang 110122, Liaoning, China

Abstract

Dural defects are a common problem in clinical practice, and various types of dural substitutes have been used to deal with dural defects. These play an important role in dural repair. Dural substitutes have gradually reached researchers, neurosurgeons, and patients for approval. This article summarizes the structural characteristics of the dura mater and its regeneration after injury, and reviews the state of progress in research and application. It will provide a reference for the development and application of dural substitutes.

Keywords: reconstruction, dural substitutes, dural defect, materials, tissue engineering

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Publication history
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Publication history

Received: 18 June 2019
Revised: 26 September 2019
Accepted: 04 November 2019
Published: 29 November 2019
Issue date: December 2019

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© The authors 2019

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This article is published with open access at http://jnr.tsinghuajournals.com

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