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Research Article | Open Access | Just Accepted

Progress in the study of ameliorative effects of medicinal and edible plants based on various active ingredients on non-alcoholic fatty liver disease

Yingjie Zhanga,Ziling Wanga,Jiahe Daia,b,cChongying Shia,b,cJun Shenga,b,cYang Tiana,b,c,d ( )Liang Taoa,b,c( )

a College of Food Science and Technology, Yunnan Agricultural University, Kunming 650201, China

b Engineering Research Center for the Development and Utilization of Food and Medicine Homologous Resources, Kunming 650201, China

c Yunnan Key Laboratory of Precision Nutrition and Personalized Food Manufacturing, Yunnan Agricultural University, Kunming 650201, China

d Puer University, Puer 665000, China

These authors contributed equally to this work.

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Abstract

Nonalcoholic fatty liver disease (NAFLD) is a chronic fatty liver disease whose core mechanism lies in obesity-induced insulin resistance, adipose tissue dysfunction, accumulation of free fatty acids in the liver, and concomitant dysbiosis of the intestinal flora. In recent years, some of the active ingredients of food and drug homologous plants have significantly improved NAFLD. This paper focuses on food and medicine homologous plants with the ability to improve NAFLD. The active substances of food and medicine homologous active substances to improve NAFLD are mainly classified into five categories: polysaccharides, polyphenols, flavonoids, terpenoids and others, and their sources and categories, active substances and extraction methods are summarized and analyzed for their mechanisms of action on NAFLD. It aims to provide meaningful data and references for the study and application of food and medicine homologous plants in the treatment of NAFLD.

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Cite this article:
Zhang Y, Wang Z, Dai J, et al. Progress in the study of ameliorative effects of medicinal and edible plants based on various active ingredients on non-alcoholic fatty liver disease. Food Science and Human Wellness, 2025, https://doi.org/10.26599/FSHW.2025.9250838

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Received: 20 March 2025
Revised: 17 April 2025
Accepted: 28 July 2025
Available online: 03 December 2025

© 2025 Beijing Academy of Food Sciences. Publishing services by Tsinghua University Press.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).