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Research Article | Open Access

Formation and network relationship of 4 hazards in fried foods

Xiaofang Liua,bXiaowei XuaYinyin WuaXiangxin XuaMengyu ShenaJixian ZhangaChaoting WenaLi LiangaYoudong LiaGuoyan Liua( )Xin Xua( )
School of Food Science and Engineering, Yangzhou University, Yangzhou 225127, China
School of Tourism and Cuisine, Yangzhou University, Yangzhou 225127, China

Peer review under responsibility of Beijing Academy of Food Sciences.

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Highlights

• The formation of four hazards in fried potatoes, tofu, and chicken wings is studied.

• AA, 5-HMF, HCAs, and PAHs accumulate in food with increased heating time.

• AA, HCAs, and PAHs in chicken wings increase as the increase in frying temperature.

• Significant correlations are found between the concentrations of four hazards.

• A network relationship of four hazards formation mechanisms is established.

Abstract

Acrylamide (AA), 5-hydroxymethylfurfural (5-HMF), heterocyclic amines (HCAs), and polycyclic aromatic hydrocarbons (PAHs) are prevalent in fried foods and pose significant health risks. Our study explored the formation of these hazards in fried potatoes, tofu, and chicken wings across a range of frying temperatures. We discovered that elevated temperatures and extended oil heating durations substantially increased the formation of these hazards. Notably, AA and 5-HMF were most concentrated in potatoes, which are rich in reducing sugars, while HCAs and PAHs were particularly high in chicken wings, attributing to their high fat and protein content. Intriguingly, significant correlations were identified among the concentrations of these hazards. Further analysis unveiled a network of interconnected formation mechanisms, highlighting shared intermediates and pathways such as the Maillard reaction, lipid and protein oxidation, and sugar pyrolysis. These findings deepen our comprehension of how these hazards interrelate and form, offering valuable insights for developing strategies to reduce their concurrent formation during the frying process.

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Food Science and Human Wellness
Article number: 9250526

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Cite this article:
Liu X, Xu X, Wu Y, et al. Formation and network relationship of 4 hazards in fried foods. Food Science and Human Wellness, 2026, 15(7): 9250526. https://doi.org/10.26599/FSHW.2025.9250526

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Received: 25 September 2024
Revised: 17 November 2024
Accepted: 16 January 2025
Published: 07 August 2026
© 2026 Beijing Academy of Food Sciences. Publishing services by Tsinghua University Press.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).