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Review | Open Access

Methods of preparation, structural characteristics of resistant starch and its relation to human health: a review

Weiyi Zhang1Yang Yang1Chunmin MaBing WangXiaofei LiuYan WangXin BianGuang ZhangNa Zhang ( )
College of Food Engineering, Harbin University of Commerce, Harbin 150028, China

1 These authors contributed equally to this work.

Peer review under responsibility of Beijing Academy of Food Sciences.

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Highlights

• The emerging preparation methods of resistant starch were reviewed.

• Changes in starch structure during the preparation of RS were discussed.

• RS alleviates chronic diseases through PI3KAktP53 signaling pathways and mitochondrial apoptotic pathway.

Abstract

Resistant starch (RS) comprises starch fractions that resist digestion in the small intestine and reach the colon, where they are fermented by the microbiota. Resistant starch harbors functional properties and health-promoting ingredients that can regulate blood glucose and lipid levels, prevent cancer, and enhance the quality of life. Consequently, new technologies for the preparation of RS are continually being developed to support its industrial production. This review describes the structural and nutritional properties of RS and examines recent advancements in RS preparation methods. Emphasis is placed on how RS structure influences its properties and the physiological mechanisms in vivo. This review aims to stimulate further research into the preparation methods, functional characteristics, and utilization of RS, thereby supporting ongoing developments in the food industry.

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Food Science and Human Wellness
Article number: 9250432

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Review Status: {{reviewData.commendedNum}} Commended , {{reviewData.revisionRequiredNum}} Revision Required , {{reviewData.notCommendedNum}} Not Commended Under Peer Review

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Cite this article:
Zhang W, Yang Y, Ma C, et al. Methods of preparation, structural characteristics of resistant starch and its relation to human health: a review. Food Science and Human Wellness, 2026, 15(4): 9250432. https://doi.org/10.26599/FSHW.2024.9250432

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Received: 21 June 2024
Revised: 29 July 2024
Accepted: 10 October 2024
Published: 12 May 2026
© 2026 Beijing Academy of Food Sciences. Publishing services by Tsinghua University Press.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).