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Open Access

Impact of phytoconstituents on oral health practices: a post COVID-19 observation

Harsh Kumara,1, Reena Singhb,1, Daljeet Singh Dhanjalb,1, Chirag Choprab,1, Natália Cruz-Martinsc,d,e,f, Gheyath K. Nasrallahg,h, Amin F. Majdalawiehi, Sivakumar Manickamj, Shahida Anusha Siddiquik, Dinesh Kumara( ), Indu Sharmal( ), Varun Sharmam( )
School of Bioengineering & Food Technology, Shoolini University of Biotechnology and Management Sciences, Solan 173229, India
School of Bioengineering and Biosciences, Lovely Professional University, Punjab 144402, India
Faculty of Medicine, University of Porto, Porto 4200-319, Portugal
Institute for Research and Innovation in Health (i3S), University of Porto, Porto 4200-135, Portugal
Institute of Research and Advanced Training in Health Sciences and Technologies (CESPU), RuaCentral de Gandra, Gandra 4585-116, Portugal
TOXRUN-Toxicology Research Unit, University Institute of Health Sciences, CESPU, CRL, Gandra 4585-116, Portugal
Biomedical Research Center, Qatar University, Doha 2713, Qatar
Department of Biomedical Science, College of Health Sciences, Qatar University, Doha 2713, Qatar
Department of Biology, Chemistry, and Environmental Sciences, College of Arts and Sciences, American University of Sharjah, Sharjah 26666, United Arab Emirates
Petroleum and Chemical Engineering, Faculty of Engineering, Universiti Teknologi Brunei, Bandar Seri Begawan BE1410, Brunei
Campus Straubing for Biotechnology and Sustainability, Technical University of Munich, Straubing 94315, Germany
Genetic Heritage Group, New York University, Abu Dhabi 129188, United Arab Emirates
Bioinformatics Division, NMC Genetics India Pvt. Ltd., Gurugram 122001, India

1 These authors contributed equally to this work.

Peer review under responsibility of Tsinghua University Press.

Show Author Information

Abstract

Appropriate oral hygiene significantly reduces the possibility of oral infections. However, dental caries and periodontal diseases are major oral health issues causing chronic diseases due to poor oral health. Recently, herbal compounds have gained interest in maintaining oral health. Extracts of burdock root (Arctium), noni fruit (Morinda citrifolia), and neem leaf (Azadirachta indica) are now used as intracanal medicaments in endodontics and periodontics. Plectranthus amboinicus species and other plants produces essential oil like β-caryophyllene, p-cymene, and γ-terpinene can exhibit antibacterial activity; highlighting phytoconstituents plays a vital role in oral health. The COVID-19 pandemic highlighted the importance of hygiene and sanitization, to curb SARS-CoV-2. Oral cavity is among the gateways for virus entry into saliva. Saliva is a potential reservoir of SARS-CoV-2, and there is an increased risk of infection if there is any fissure in the mouth. This enables entry of virus into the vascular system through gingival or periodontal pocket, possibly reaching lung periphery then to lung vessels by interacting with endothelial surface receptors triggering pulmonary vasoconstriction and lung damage due to endothelial dysfunction. This review aims to draw attention to the possible route of SARS-CoV-2 infection via the oral cavity and the importance of oral hygiene against COVID-19.

Keywords

COVID-19SARS-CoV-2OralHygieneMicrobiotaPhytochemicals

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Food Science and Human Wellness
Volume 13 Issue 5,
September 2024
Pages 2386-2400
DOI: 10.26599/FSHW.2022.9250197
Cite this article:
Kumar H, Singh R, Dhanjal DS, et al. Impact of phytoconstituents on oral health practices: a post COVID-19 observation. Food Science and Human Wellness, 2024, 13(5): 2386-2400. https://doi.org/10.26599/FSHW.2022.9250197

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Received: 17 June 2022
Revised: 14 October 2022
Accepted: 05 November 2022
Published: 10 October 2024
© 2024 Beijing Academy of Food Sciences. Publishing services by Tsinghua University Press.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
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