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Food Science and Human Wellness 2024, 13(2): 597-610 https://doi.org/10.26599/FSHW.2022.9250140
Open Access | Issue | Published: 25 September 2023

Resveratrol combats chronic diseases through enhancing mitochondrial quality

Show Author's Information Weichu Taoa,1,  Hu Zhanga,1,  Xia Jiangb( ),  Ning Chena,( )
Tianjiu Research and Development Center for Exercise Nutrition and Foods, Hubei Key Laboratory of Exercise Training and Monitoring, College of Sports Medicine, Wuhan Sports University, Wuhan 430079, China
The University Hospital of Wuhan Sports University, Wuhan 430079, China

1 These authors have contributed equally to this work.

Peer review under responsibility of Tsinghua University Press.

Keywords:
Anti-oxidation, Resveratrol, Chronic disease, Functional food, Mitochondrial quality, Anti-inf lammation
Cite this article:
Tao W, Zhang H, Jiang X, et al. Resveratrol combats chronic diseases through enhancing mitochondrial quality. Food Science and Human Wellness, 2024, 13(2): 597-610. https://doi.org/10.26599/FSHW.2022.9250140
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Abstract Full text About this article

Resveratrol (RSV), as a functional food component extracted from natural plants, has been widely studied and recognized in preventing and treating various diseases, with major mechanisms including executing anti-inflammation and anti-oxidation functions, and improving mitochondrial quality. Chronic diseases as non-communicable diseases are mainly caused by multiple factors, such as physiological decline and dysfunction in the body, and have become a significant challenge on public health worldwide. It is worth noting that chronic diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD), muscle atrophy, cardiovascular disease, obesity, and cancer are accompanied by abnormal mitochondrial function. Therefore, targeted regulation of mitochondria may be a meaningful way to prevent and treat chronic diseases. Increasing evidence has confirmed that RSV is actively involved in regulating mitochondria, and it has become an essential consideration to prevent and treat chronic diseases through targeting mitochondria and improving corresponding functions. In this article, current studies on RSV to optimize mitochondrial quality for preventing and alleviating chronic disease are systematically summarized, which can provide a theoretical reference for the development of functional foods or drugs to combat chronic diseases.


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About this article

Resveratrol combats chronic diseases through enhancing mitochondrial quality

Show Author's information Weichu Taoa,1, Hu Zhanga,1, Xia Jiangb( ), Ning Chena,( )
Tianjiu Research and Development Center for Exercise Nutrition and Foods, Hubei Key Laboratory of Exercise Training and Monitoring, College of Sports Medicine, Wuhan Sports University, Wuhan 430079, China
The University Hospital of Wuhan Sports University, Wuhan 430079, China

1 These authors have contributed equally to this work.

Peer review under responsibility of Tsinghua University Press.

Abstract

Resveratrol (RSV), as a functional food component extracted from natural plants, has been widely studied and recognized in preventing and treating various diseases, with major mechanisms including executing anti-inflammation and anti-oxidation functions, and improving mitochondrial quality. Chronic diseases as non-communicable diseases are mainly caused by multiple factors, such as physiological decline and dysfunction in the body, and have become a significant challenge on public health worldwide. It is worth noting that chronic diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD), muscle atrophy, cardiovascular disease, obesity, and cancer are accompanied by abnormal mitochondrial function. Therefore, targeted regulation of mitochondria may be a meaningful way to prevent and treat chronic diseases. Increasing evidence has confirmed that RSV is actively involved in regulating mitochondria, and it has become an essential consideration to prevent and treat chronic diseases through targeting mitochondria and improving corresponding functions. In this article, current studies on RSV to optimize mitochondrial quality for preventing and alleviating chronic disease are systematically summarized, which can provide a theoretical reference for the development of functional foods or drugs to combat chronic diseases.

Keywords: Anti-oxidation, Resveratrol, Chronic disease, Functional food, Mitochondrial quality, Anti-inf lammation

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Publication history

Received: 05 May 2023
Revised: 05 June 2023
Accepted: 14 June 2023
Published: 25 September 2023
Issue date: March 2024

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© 2024 Beijing Academy of Food Sciences. Publishing services by Tsinghua University Press.

Acknowledgements

Acknowledgements

This work was supported by the National Natural Science Foundation of China (No. 32071176), the 14th Five-Year-Plan Advantageous and Characteristic Disciplines (Groups) of Colleges and Universities in Hubei Province for Exercise and Brain Science from Hubei Provincial Department of Education and the Chutian Scholar Program and Innovative Start-Up Foundation from Wuhan Sports University to Ning Chen.

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This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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