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Review Article | Open Access

Weizmannia coagulans: an ideal probiotic for gut health

Shiqi Zhanga,bPinglan Lia,cSuwon LeebYu WangaChunming Tana,cNan Shangc,d ( )
Key Laboratory of Functional Dairy, Ministry of Education, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China
Coree Beijing Co., Ltd., Beijing 101312, China
Key Laboratory of Precision Nutrition and Food Quality, Department of Nutrition and Health, China Agricultural University, Beijing 100083, China
College of Engineering, China Agricultural University, Beijing 100083, China

Peer review under responsibility of Tsinghua University Press.

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Abstract

Weizmannia coagulans (formerly Bacillus coagulans) is a spore-forming and lactic acid-producing bacterium. It has recently attracted much attention from researchers and food manufacturers due to its probiotic functions and stability in processing and storage. W. coagulans is capable of improving gut health through the regulation of gut microbiota, modulation of immunity, and improving digestibility and metabolism. Spores, germinated cells and metabolites of W. coagulans modulate the gut micro-environment and further affect other organs. W. coagulans is an environment-friendly probiotic since it can contribute to the host by reconstructing the balance of gut microbiota and only temporarily resides in the intestine after administration. W. coagulans has been generally recognized as safe (GRAS) by the US Food and Drug Administration (FDA), thus it is an ideal probiotic for improving gut health. The merit of its stability in processing and storage provides W. coagulans spores many possibilities for its use in various types of functional foods. This review presents an overview of the characteristics of W. coagulans that make it an ideal probiotic candidate and highlights the proposed health benefits with scientific evidence conferred by the administration of W. coagulans.

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Food Science and Human Wellness
Pages 16-26

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Cite this article:
Zhang S, Li P, Lee S, et al. Weizmannia coagulans: an ideal probiotic for gut health. Food Science and Human Wellness, 2024, 13(1): 16-26. https://doi.org/10.26599/FSHW.2022.9250002

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Received: 25 July 2022
Revised: 26 August 2022
Accepted: 22 September 2022
Published: 01 June 2023
© 2024 Beijing Academy of Food Sciences. Publishing services by Tsinghua University Press.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).