The immunomodulatory effect of milk-derived bioactive peptides on food allergy: a review

Fen Xie; Huming Shao; Jinyan Gao; Xuanyi Meng; Yong Wu; Hongbing Chen; Xin Li

doi:10.26599/FSAP.2023.9240018

Food Science of Animal Products 2023, 1(2): 9240018 https://doi.org/10.26599/FSAP.2023.9240018

Review Article |

Open Access | Issue | Published: 17 July 2023

The immunomodulatory effect of milk-derived bioactive peptides on food allergy: a review

Show Author's Information Hide Author's Information Fen Xie^{¹^,²}, Huming Shao^{¹^,²}, Jinyan Gao^{¹^,²^,³}, Xuanyi Meng^{¹^,³^,⁴}, Yong Wu^{¹^,³^,⁴}, Hongbing Chen^{¹^,³^,⁴}, Xin Li^{¹^,²^,³}(

)

1State Key Laboratory of Food Science and Resources, Nanchang University, Nanchang 330047, China

2School of Food Science and Technology, Nanchang University, Nanchang 330047, China

3Jiangxi Provincial Key Laboratory of Food Allergy, Nanchang University, Nanchang 330047, China

4Sino-German Joint Research Institute, Nanchang University, Nanchang 330047, China

Keywords:

inflammation, immunomodulation, bioactive peptides, food allergy, milk

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Xie F, Shao H, Gao J, et al. The immunomodulatory effect of milk-derived bioactive peptides on food allergy: a review. Food Science of Animal Products, 2023, 1(2): 9240018. https://doi.org/10.26599/FSAP.2023.9240018

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Abstract Full text About this article

Abstract

Bioactive peptides (BPs) not only have nutritional value, but also have a wide range of biological activities, such as opioid activity, antibacterial activity, antioxidant properties and immunomodulatory which were associated with potential health benefits. Milk-derived BPs are the most researched, deepest and most widely used food-derived BPs. Milk-derived BPs perform an increasingly important role in regulating inflammatory balance in food allergy (FA) due to the immunomodulatory effect. This review outlines its immunomodulatory role in FA around cytokine level and gut regulation, and also emphasizes the production methods and current market applications of milk-derived BPs.

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About this article

The immunomodulatory effect of milk-derived bioactive peptides on food allergy: a review

Show Author's information Hide Author's Information Fen Xie^{¹^,²}, Huming Shao^{¹^,²}, Jinyan Gao^{¹^,²^,³}, Xuanyi Meng^{¹^,³^,⁴}, Yong Wu^{¹^,³^,⁴}, Hongbing Chen^{¹^,³^,⁴}, Xin Li^{¹^,²^,³}(

)

1State Key Laboratory of Food Science and Resources, Nanchang University, Nanchang 330047, China

2School of Food Science and Technology, Nanchang University, Nanchang 330047, China

3Jiangxi Provincial Key Laboratory of Food Allergy, Nanchang University, Nanchang 330047, China

4Sino-German Joint Research Institute, Nanchang University, Nanchang 330047, China

Abstract

Keywords: inflammation, immunomodulation, bioactive peptides, food allergy, milk

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Acknowledgements

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Publication history

Received: 03 May 2023

Revised: 12 June 2023

Accepted: 13 June 2023

Published: 17 July 2023

Issue date: June 2023

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Acknowledgements

This study was supported by National Natural Science Foundation of China (32072241), Research Project of State Key Laboratory of Food Science and Technology, Nanchang University (SKLF-ZZB-202120 and SKLF-KF-202205), Central Government Guide Local Special Fund Project for Scientific and Technological Development of Jiangxi Province (20221ZDD02001), Special Project for Research and Development in Key Areas of Guangdong Province (2022B0202030002), and Special Innovation Project of Postgraduate of Jiangxi Province (YC2022-s002).

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Food Science of Animal Products published by Tsinghua University Press. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).