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Review Article | Open Access

Current progress in protein requirement changes and associated factors in the aging population

Si-Ying Tu1Xiao-Yu Hao1Shan Xu1Wang Liao1Hui Xia1Shao-Kang Wang1,2 ( )Gui-Ju Sun1
Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, Department of Nutrition and Food Hygiene, School of Public Health, Southeast University, Nanjing 210009, China
Clinical Medical Research Center for Plateau Gastroenterological Disease of Xizang Autonomous Region, School of Medicine, Xizang Minzu University, Xianyang 712082, China
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Highlights

(1) Suggested how different protein intake impacts muscle morphology and function.

(2) Short-term reductions in protein intake lead to alterations in muscle mRNA concentrations.

(3) Barriers to adequate protein consumption include limited access to nutrient-dense foods, insufficient nutritional education, and prevalent misconceptions about dietary needs in the aging population.

Abstract

This review provides a comprehensive analysis of the importance of protein intake among older adults. With the global aging trend accelerating, adequate protein consumption is increasingly recognized as crucial for addressing the decline in muscle mass and function associated with aging. Research has shown that older adults require a higher protein intake (1.0−1.3 g/(kg∙day)) to maintain muscle health, although the optimal recommendation remains a topic of ongoing investigation. The review highlights that the protein needs of older adults are often unmet by the recommended dietary allowance (RDA), potentially leading to health issues such as sarcopenia, weakened immune function, and delayed wound healing. Additionally, it examines various factors influencing protein intake in older adults, including socioeconomic status, education level, geographic location, and individual health conditions. The review also explores dietary patterns and protein sources, including both animal-based and plant-based proteins, and their effects on muscle protein synthesis (MPS). Finally, it underscores the critical role of sufficient protein intake in preserving the health, functionality, and quality of life of older adults, emphasizing the need for public health initiatives to address inadequate protein consumption in this population.

Graphical Abstract

This graphical abstract summarizes recent advances in protein requirements and influencing factors in the elderly population. Education, geographic location, and financial status influence intake, which often remains below optimal levels. The Chinese Nutrition Society (2023) now recommends 1.0–1.2 g/kg/day, higher than the traditional 0.8 g/kg/day. Muscle outcomes improve with ≥1.2 g/kg/day, while intakes above 1.6–1.9 g/kg/day show diminishing benefit. Protein source also plays a role: animal protein, rich in leucine, stimulates muscle protein synthesis but may increase cardiovascular risk; plant protein, though limited in lysine and methionine, appears cardioprotective. At ~1.15 g/kg/day, source-related differences are minimized.

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Food & Medicine Homology
Article number: 9420136

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Cite this article:
Tu S-Y, Hao X-Y, Xu S, et al. Current progress in protein requirement changes and associated factors in the aging population. Food & Medicine Homology, 2026, 3(3): 9420136. https://doi.org/10.26599/FMH.2026.9420136

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Received: 09 October 2024
Revised: 18 November 2024
Accepted: 29 November 2024
Published: 10 February 2026
© National R & D Center for Edible Fungus Processing Technology 2026. Published by Tsinghua University Press.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).